Structurally Aligned Multifunctional Neural Probe (SAMP) Using Forest‐Drawn CNT Sheet onto Thermally Drawn Polymer Fiber for Long‐Term In Vivo Operation
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Le résumé fourni par la source
Neural probe engineering is a dynamic field, driving innovation in neuroscience and addressing scientific and medical demands. Recent advancements involve integrating nanomaterials to improve performance, aiming for sustained in vivo functionality. However, challenges persist due to size, stiffness, complexity, and manufacturing intricacies. To address these issues, a neural interface utilizing freestanding CNT-sheets drawn from CNT-forests integrated onto thermally drawn functional polymer fibers is proposed. This approach yields a device with structural alignment, resulting in exceptional electrical, mechanical, and electrochemical properties while retaining biocompatibility for prolonged periods of implantation. This Structurally Aligned Multifunctional neural Probe (SAMP) employing forest-drawn CNT sheets demonstrates in vivo capabilities in neural recording, neurotransmitter detection, and brain/spinal cord circuit manipulation via optogenetics, maintaining functionality for over a year post-implantation. The straightforward fabrication method's versatility, coupled with the device's functional reliability, underscores the significance of this technique in the next-generation carbon-based implants. Moreover, the device's longevity and multifunctionality position it as a promising platform for long-term neuroscience research.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Structurally Aligned Multifunctional Neural Probe (SAMP) Using Forest‐Drawn CNT Sheet onto Thermally Drawn Polymer Fiber for Long‐Term In Vivo Operation
- Date Crossref
- 08/04/2024
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Korea Advanced Institute of Science and Technology Department of Bio and Brain Engineering pays non établi dans la noticeUniversité ou école supérieure
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Hanyang University Department of Electronic Engineering and Biomedical Engineering pays non établi dans la noticeUniversité ou école supérieure
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Sungkyunkwan University Department of Energy Science pays non établi dans la noticeUniversité ou école supérieure
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Ulsan National Institute of Science and Technology Department of Biomedical Engineering pays non établi dans la noticeUniversité ou école supérieure
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KAIST Institute for NanoCentury (KINC) Daejeon 34141 Republic of Korea pays non établi dans la noticeStructure de recherche
Department of Bio and Brain Engineering — Korea Advanced Institute of Science and Technology, Department of Electronic Engineering and Biomedical Engineering — Hanyang University et Department of Energy Science — Sungkyunkwan University, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.