18F-FDG PET/CT Correctly Differentiates Idiopathic Pericarditis From Recurrent Lymphoma in a Patient with Primary Mediastinal Lymphoma

Résumé fourni par la source

A man in his 30s awaiting end-of-treatment 18 F-fluorodeoxyglucose positron emission tomography/CT ( 18 F-FDG PET/CT) for primary mediastinal B-cell lymphoma developed chest pain and pericardial effusion.His interim 18 F-FDG PET/CT showed complete metabolic responses.His blood test revealed elevated levels of inflammatory markers, including C-reactive protein of 204.1 mg/L and erythrocyte sedimentation rate of 106 mm/h.His pericardial biopsy revealed organizing fibrinous pericarditis with hemosiderin pigment deposition and no evidence of malignancy or granuloma.The 18 F-FDG PET/CT performed during this episode of illness revealed a mild degree of 18 F-FDG uptake along the pericardial lining [maximum standardized uptake value (SUV max ) =6.76] compared with the blood pool activity (SUV max =3.17), which favors pericarditis over relapsed lymphoma.His symptoms subsided 2 weeks after treatment with an non-steroidal anti-inflammatory drug, and he had no sign of relapsed lymphoma on subsequent follow-ups.

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