Utilidad diagnóstica y pronóstica de la clasificación molecular en gliomas de alto grado

Le résumé fourni par la source

According to the 5th edition (2021) of the World Health Organization Classification of Primary Tumors of the Central Nervous System, to adequately categorize these neoplasms, it is necessary to evaluate both histological and molecular characteristics. Clinical cases: a descriptive study was implemented for a series of 4 cases with histological diagnosis of high-grade glioma, in whom next-generation sequencing was performed, which led to a comparison between methodologies and highlighting the importance of the use of biology molecular basis for the classification of these neoplasms. A modification was generated in the initial taxonomic classification carried out by histopathology, resulting in a change not only in the diagnosis but also in the prognosis. Conclusion: the new molecular classification of high-grade gliomas specifies the diagnosis and prognosis of patients.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.