Accès ouvert déclaré
2024
article
Changes in atherosclerotic cardiovascular disease risk over time among people living with HIV
Weisi Chen, Kathy Petoumenos, Agus Somia, Natalie Edmiston, Romanee Chaiwarith, Ian Woolley, Jeremy Ross, Sanjay Pujari, David Boettiger, V. Khol, Vara Ouk, C Pov, Phnom Penh, FJ Zhang, Hong Zhao, Nana Han, MP Lee, P C K Li, Tsung-yan Kwong, T H Li, N Kumarasamy, C Ezhilarasi, Kedar Joshi, S Gaikwad, Abhishek Chitalikar, R. Borse, Vidya Mave, Ivan Marbaniang, Smita Nimkar, I Ketut Agus Somia, Tuti Parwati Merati, A.A.S. Sawitri, Fina Yuliana, Evy Yunihastuti, Alvina Widhani, T H Karjadi, Junko Tanuma, Shinichi Oka, Takeshi Nishijima, Jun Yong Choi, Narva Andrew S., Jeong‐Min Kim, Y M Gani, Núria Rudi, Iskandar Azwa, Adeeba Kamarulzaman, Shahed Omar, Sasheela Ponnampalavanar, Rossana Ditangco, Mark KU Pasayan, Mary Lorraine Mationg, H P Chen, Y J Chan, Po-Chang Wu, E Ke, Owen Ng, P L Lim, Lee Ls, Timothy A. Yap, Anchalee Avihingsanon, Sivaporn Gatechompol, Praphan Phanuphak, Chowalit Phadungphon, Sasisopin Kiertiburanakul, Angsana Phuphuakrat, L. Chumla, N. Sanmeema, Thira Sirisanthana, J Praparattanapan, Khanuengnit Nuket, S. Khuwuwan, P. Kambua, S Pongrapass, J Limlertchareonwanit, T N Pham, Kattia Valentine Nguyen, D.T. Nguyen, Carvalho Braga D, AnhL Ngo, Lich Nguyen, A Sohn, J.L. Ross, B. Petersen, Matthew Law, Awachana Jiamsakul, Dhanushi Rupasinghe, Deborah A. Ellis, Mark Bloch, Debbie Allen, Lindsay Burton, Danial E. Baker, Roya Anahita Mousavi, H Farlow, E. Jane Byrne, David J. Templeton, Linda Garton, Tracy J. Doyle, Eva Jackson, Nathan Ryder, Gary Sweeney, Brendan Moran, Andrew Carr, Karl Hesse, Anna L. Hawkes, Robert Finlayson, Michael D. Shields, Roy H. Burdon, P Calleia, Katherine Brown, Rick Varma, Rohan I. Bopage, John Walsh, Sarah Varghese, Christine Chung, Don Smith, Aaron Cogle, Christopher Lawrence, Brian P. Mulhall, Jolie Hutchinson, Norman Rose, Timothy Dougherty, D Byonanebye, Ahram Han, Darren Russell, Micaela Rodriguez, David Sowden, Kuong Taing, Jennifer Broom, Sarah Dennien, David N. Orth, D Youds, Eugene Priscott, S Benn, Eric P. Griggs, N Roth, H. Lau, R H Teague, J Silvers, Weihua Zeng, Andrew S. Levey, Jennifer Hoy, Michelle Giles, Mark Bryant, Susanna Price, P Rawson Harris, Tony M. Korman, Jess O’Bryan, Kathryn Cisera, Nigel Raymond
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Résumé fourni par la source
OBJECTIVE: To describe changes in atherosclerotic cardiovascular disease (ASCVD) risk over time among people living with HIV (PLHIV). METHODS: We used data from the TREAT Asia HIV Observational Database (TAHOD) and the Australian HIV Observational Database (AHOD). Five-year ASCVD risk was calculated using the D:A:D equation. Individuals were eligible for inclusion if they were aged ≥18 years, had started ART, had no previous history of ASCVD and had complete ASCVD risk factor data available within the first 5 years of ART initiation. RESULTS: A total of 3368 adults contributed data, 3221 were from TAHOD and 147 were from AHOD. The median age at ART initiation was 36 [IQR 31-43] years for TAHOD participants, and 42 [IQR 35-50] years for AHOD participants. Most TAHOD (70.4%) and AHOD (91.8%) participants were male. Overall, ASCVD risk increased from 0.84% (95% CI 0.81%-0.87%) at ART initiation to 1.34% (95% CI 1.29%-1.39%) after 5 years on ART. After adjusting for traditional and HIV-associated ASCVD risk factors, ASCVD risk increased at a similar rate among sub-populations defined by HIV exposure (heterosexuals, men who have sex with men, people who inject drugs), race/ethnicity (Caucasian and Asian) and nadir CD4 at ART initiation (<200 and ≥200 cells/mm3). CONCLUSIONS: These findings emphasize the growing burden of ASCVD risk among PLHIV and the need to develop interventions that are effective across a broad range of HIV sub-populations.
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Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Changes in atherosclerotic cardiovascular disease risk over time among people living with HIV
- Date Crossref
- 28/02/2024
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
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Sujets associés
HIV-related health complications and treatmentsDiabetes, Cardiovascular Risks, and LipoproteinsLipoproteins and Cardiovascular Health