Human Papillomavirus (HPV) Infection and Risk Behavior in Vaccinated and Non-Vaccinated Paraguayan Young Women
Rattachement africain : py, br, ar. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Cervical cancer is a global health concern and ranks fourth among the most prevalent cancers in women worldwide. Human papillomavirus (HPV) infection is a known precursor of cervical cancer and preventive measures include prophylactic vaccines. This study focused on sexually active Paraguayan women aged 18–25 years, exploring the intersection of HPV vaccination and sexual behavior. Among 254 participants, 40.9% received the Gardasil-4 vaccine, with no significant differences in sexual behavior between the vaccinated and unvaccinated sexually active groups. However, a notable decrease in the prevalence of HPV among the vaccinated women highlights the efficacy of this vaccine in reducing infections. The prevalence of any HPV type was 37.5% in vaccinated participants compared to 56.7% in unvaccinated participants (p = 0.0026). High-risk HPV types showed a significant difference, with a prevalence of 26.0% in vaccinated women compared with 52.7% in unvaccinated women (p < 0.001). Although a potential decline in genital warts was observed among the vaccinated individuals, statistical significance (p = 0.0564) was not reached. Despite the challenges in achieving high vaccination coverage, the observed reduction in HPV prevalence underscores the importance of ongoing monitoring, healthcare professional recommendations, and comprehensive risk management. These findings contribute to dispelling concerns about HPV vaccination influencing sexual behavior, advocating further large-scale research to explore the impact of vaccines on various HPV types and potential cross-protection.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Human Papillomavirus (HPV) Infection and Risk Behavior in Vaccinated and Non-Vaccinated Paraguayan Young Women
- Date Crossref
- 27/02/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Ministerio de Salud Pública y Bienestar Social pays non établi dans la noticeOrganisme public
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Fundação Oswaldo Cruz pays non établi dans la noticeStructure de recherche
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National University of the Northeast pays non établi dans la noticeUniversité ou école supérieure
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Laboratory of Immunology pays non établi dans la noticeStructure de recherche
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Laboratory of Molecular Virology and Parasitology pays non établi dans la noticeStructure de recherche
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Expanded Immunization Program pays non établi dans la noticeInstitution
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Faculty of Medicine Molecular Applications Laboratory pays non établi dans la noticeUniversité ou école supérieure
Ministerio de Salud Pública y Bienestar Social, Fundação Oswaldo Cruz et National University of the Northeast, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.