Success of the US Veterans Health Administration's Hepatitis C Virus Care Continuum in the Direct-acting Antiviral Era
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Le résumé fourni par la source
BACKGROUND: Estimated hepatitis C prevalence within the Veterans Health Administration is higher than the general population and is a risk factor for advanced liver disease and subsequent complications. We describe the hepatitis C care continuum within the Veterans Health Administration 1 January 2014 to 31 December 2022. METHODS: We included individuals in Veterans Health Administration care 2021-2022 who were eligible for direct-acting antiviral treatment 1 January 2014 to 31 December 2022. We evaluated the proportion of Veterans who progressed through each step of the hepatitis C care continuum, and identified factors associated with initiating direct-acting antivirals, achieving sustained virologic response, and repeat hepatitis C viremia. RESULTS: We identified 133 732 Veterans with hepatitis C viremia. Hepatitis C treatment was initiated in 107 134 (80.1%), with sustained virologic response achieved in 98 136 (91.6%). In those who achieved sustained virologic response, 1097 (1.1%) had repeat viremia and 579 (52.8%) were retreated for hepatitis C. Veterans of younger ages were less likely to initiate treatment and achieve sustained virologic response, and more likely to have repeat viremia. Stimulant use and unstable housing were negatively associated with each step of the hepatitis C care continuum. CONCLUSIONS: The Veterans Health Administration has treated 80% of Veterans with hepatitis C in care 2021-2022 and achieved sustained virologic response in more than 90% of those treated. Repeat viremia is rare and is associated with younger age, unstable housing, opioid use, and stimulant use. Ongoing efforts are needed to reach younger Veterans, and Veterans with unstable housing or substance use disorders.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Success of the US Veterans Health Administration's Hepatitis C Virus Care Continuum in the Direct-acting Antiviral Era
- Date Crossref
- 27/01/2024
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Portland State University pays non établi dans la noticeUniversité ou école supérieure
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Oregon Health & Science University Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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University of Washington Department of Health Systems and Population Health pays non établi dans la noticeUniversité ou école supérieure
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VA Puget Sound Health Care System pays non établi dans la noticeÉtablissement de santé
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Emory University Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Atlanta VA Health Care System pays non établi dans la noticeÉtablissement de santé
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VA Long Beach Healthcare System pays non établi dans la noticeÉtablissement de santé
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VA Great Lakes Health Care System pays non établi dans la noticeÉtablissement de santé
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VA Portland Health Care System pays non établi dans la noticeÉtablissement de santé
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School of Public Health pays non établi dans la noticeUniversité ou école supérieure
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Health Systems Research pays non établi dans la noticeInstitution
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Department of Medicine pays non établi dans la noticeInstitution
Portland State University, Department of Medicine — Oregon Health & Science University et Department of Health Systems and Population Health — University of Washington, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.