Encapsulated phenolic compounds: clinical efficacy of a novel delivery method
Rattachement africain : tr, in, it, cn. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Encapsulation is a drug or food ingredient loaded-delivery system that entraps active components, protecting them from decomposition/degradation throughout the processing and storage stages and facilitates their delivery to the target tissue/organ, improving their bioactivities. The application of this technology is expanding gradually from pharmaceuticals to the food industry, since dietary bioactive ingredients, including polyphenols, are susceptible to environmental and/or gastrointestinal conditions. Polyphenols are the largest group of plants' secondary metabolites, with a wide range of biological effects. Literature data have indicated their potential in the prevention of several disorders and pathologies, ranging from simpler allergic conditions to more complex metabolic syndrome and cardiovascular and neurodegenerative diseases. Despite the promising health effects in preclinical studies, the clinical use of dietary polyphenols is still very limited due to their low bioaccessibility and/or bioavailability. Encapsulation can be successfully employed in the development of polyphenol-based functional foods, which may improve their bioaccessibility and/or bioavailability. Moreover, encapsulation can also aid in the targeted delivery of polyphenols and may prevent any possible adverse events. For the encapsulation of bioactive ingredients, several techniques are applied such as emulsion phase separation, emulsification/internal gelation, film formation, spray drying, spray-bed-drying, fluid-bed coating, spray-chilling, spray-cooling, and melt injection. The present review aims to throw light on the existing literature highlighting the possibility and clinical benefits of encapsulated polyphenols in health and disease. However, the clinical data is still very scarce and randomized clinical trials are needed before any conclusion is drawn. Graphical abstract
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Encapsulated phenolic compounds: clinical efficacy of a novel delivery method
- Date Crossref
- 27/01/2024
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Istanbul Technical University pays non établi dans la noticeUniversité ou école supérieure
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Istanbul Arel University pays non établi dans la noticeUniversité ou école supérieure
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JSS Academy of Higher Education and Research pays non établi dans la noticeUniversité ou école supérieure
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JSS College of Pharmacy Department of Pharmacognosy pays non établi dans la noticeUniversité ou école supérieure
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University of Naples Federico II Department of Pharmacy pays non établi dans la noticeUniversité ou école supérieure
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Jiangsu University International Research Centre for Food Nutrition and Safety pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Chemical and Metallurgical Engineering Department of Food Engineering pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Engineering Department of Food Engineering pays non établi dans la noticeUniversité ou école supérieure
Istanbul Technical University, Istanbul Arel University et JSS Academy of Higher Education and Research, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.