Tunable glycyrrhizic acid supramolecular hydrogels via metal ion complexation
Rattachement africain : cn, nl, hk. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Glycyrrhizic acid (GA) is a natural edible chiral triterpene saponin that can undergo hierarchical self-assembly in water to form supramolecular hydrogels. Customizing the properties of GA supramolecular hydrogels is crucial for their wide food and biomedical applications, and the incorporation of specific metal ions can be an attractive way for this purpose. Herein, this study investigates the effects of metal ions with different valence states and concentrations on the linear and nonlinear rheological properties and network structures of GA supramolecular hydrogels. Monovalent metal ions (Na+ and K+), exhibiting weak binding affinity to GA, rely on the electrostatic screening effects at high concentrations (e.g., 50 mM) to enhance the GA interfibrillar interactions and thus the formation of a more compact and ordered gel network, which displays a pronounced nonlinear rheological behavior with a typical transition from elastic to viscous response. Polyvalent metal ions (Ca2+, Zn2+, and Al3+), owing to their greater charge density and stronger binding with GA, significantly enhance the network strength of the hydrogels at low concentrations (e.g., 5 mM). Nonetheless, at high ion concentrations (e.g., 50 mM), the GA-Mn+ forms discrete aggregated network structures due to excessively strong cation-carboxylate complexation, leading to the irregular nonlinear rheological responses and the lower resistance to large deformations. These findings can deepen our understanding of the highly tunable rheological behaviors and network structures of GA hydrogels, which demonstrates a new possibility for the design and development of responsive natural supramolecular hydrogels with controlled properties through the strategy of metal ion complexation.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Tunable glycyrrhizic acid supramolecular hydrogels via metal ion complexation
- Date Crossref
- 01/03/2024
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety pays non établi dans la noticeStructure de recherche
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South China University of Technology pays non établi dans la noticeUniversité ou école supérieure
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Wageningen University & Research Laboratory of Physics and Physical Chemistry of Foods pays non établi dans la noticeUniversité ou école supérieure
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Innovation Team (China) pays non établi dans la noticeEntreprise
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School of Food Science and Engineering Laboratory of Food Proteins and Colloids pays non établi dans la noticeUniversité ou école supérieure
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Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center) pays non établi dans la noticeInstitution
Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology et Laboratory of Physics and Physical Chemistry of Foods — Wageningen University & Research, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.