COPD in Never-Smokers: BOLD Australia Study

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Purpose: Tobacco smoking is the major risk factor for COPD, and it is common for other risk factors in never-smokers to be overlooked. We examined the prevalence of COPD among never-smokers in Australia and identified associated risk factors. Methods: We used data from the Australia Burden of Obstructive Lung Disease (BOLD) study, a cross-section of people aged ≥ 40 years from six sites. Participants completed interviews and post-bronchodilator spirometry. COPD was primarily defined as an FEV 1 /FVC ratio < 0.70 and secondarily as the ratio less than the lower limit of normal (LLN). Results: The prevalence of COPD in the 1656 never-smokers who completed the study was 10.5% (95% CI: 9.1– 12.1%) [ratio Conclusion: COPD was prevalent in this population of never-smokers aged 40 years and over. This finding highlights the significance of risk factors other than smoking in the development of COPD. Keywords: non-smokers, prevalence, spirometry, lower limit of normal, LLN, burden of obstructive lung disease, BOLD

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