Molecular biology of nephroblastoma in the context of kidney development

Le résumé fourni par la source

This paper presents a literature review of nephroblastoma molecular biology. In this article, we explored protein-coding genes in which mutations are the most common cause of Wilms’ tumor. We analyzed the role of these genes both in normal renal development and in Wilms’ tumorigenesis. Our special attention was focused on the embryonic development of the kidneys and how mutations in certain genes can disrupt normal nephrogenesis leading to the emergence of nephroblastoma.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.