Revitalizing the skin: Exploring the role of barrier repair moisturizers
Rattachement africain : in. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Moisturizers are designed to maintain skin health and treat dermatological conditions associated with impaired skin barrier function. However, differences in their composition account for the differences in their effect. AIMS: This narrative review aims to discuss the role of barrier repair moisturizers, highlight the role of different components in a moisturizer and their role in impaired skin conditions (e.g., dry, itchy, inflamed, sensitive skin, atopic eczema), and thereby empower dermatologists and pediatricians in selecting the right moisturizer. METHODS: PubMed, Embase, and Scopus electronic databases were searched from January 2000 to June 2023 for publications on skin barrier repair and use of barrier repair moisturizers for the treatment of dry, itchy, inflamed, sensitive skin, or atopic eczema. Studies conducted in humans, published in English for which full texts were freely available were included. RESULTS: The structure and composition of lipid lamellae within the stratum corneum play an important role in maintaining an effective skin barrier and protecting the body from various external assaults. Endocannabinoid mediators play an active role in maintaining skin barrier function. Moisturizers containing physiological lipids and functional ingredients (e.g., endocannabinoids such as palmitoylethanolamide [PEA]) and based on the principles of biomimic technology are demonstrated to be beneficial for the management of conditions associated with a disrupted skin barrier. CONCLUSIONS: Moisturizer based on the innovative biomimic formulation has good cosmetic efficacy and is generally well tolerated, and the addition of PEA might represent a new generation of compounds that may be beneficial for long-term management of impaired skin conditions.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Revitalizing the skin: Exploring the role of barrier repair moisturizers
- Date Crossref
- 12/01/2024
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Sir H.N. Reliance Foundation Hospital and Research Centre pays non établi dans la noticeÉtablissement de santé
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P. D. Hinduja Hospital and Medical Research Centre pays non établi dans la noticeÉtablissement de santé
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National Hospital Department Coordinator pays non établi dans la noticeÉtablissement de santé
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GlaxoSmithKline (India) pays non établi dans la noticeEntreprise
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Cutis Skin and Laser Centre Nerul Navi Mumbai India pays non établi dans la noticeInstitution
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GSK Mumbai India pays non établi dans la noticeInstitution
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GSK Bengaluru India pays non établi dans la noticeInstitution
Sir H.N. Reliance Foundation Hospital and Research Centre, P. D. Hinduja Hospital and Medical Research Centre et Department Coordinator — National Hospital, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.