Risk of Postoperative Ischemic Stroke and Myocardial Infarction in Patients Operated for Cancer
Rattachement africain : se, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Risk assessment for ischemic stroke (IS) and myocardial infarction (MI) is done routinely before surgery, but the increase in risks associated with surgery is not known. The aim of this study is to assess the risk of arterial ischemic events during the first year after oncological surgery. METHODS: We used Swedish healthcare databases to identify 443,300 patients who underwent cancer surgery between 1987 and 2016 and 4,127,761 matched comparison subjects. We estimated odds ratios (ORs) for myocardial infarction and ischemic stroke during the hospitalization with logistic regression and calculated 1-year cumulative incidences and hazard ratios (HRs) with 95% confidence intervals (CIs) for the outcomes after discharge. RESULTS: The cumulative incidences of myocardial infarction and ischemic stroke during the first postoperative year were 1.33% and 1.25%, respectively. In the comparison cohort, the corresponding 1-year cumulative incidences were 1.04% and 1.00%. During the hospitalization, the OR for myocardial infarction was 8.81 (95% CI 8.24-9.42) and the OR for ischemic stroke was 6.71 (95% CI 6.22-7.23). After discharge, the average HR during follow-up for 365 days was 0.90 (95% CI 0.87-0.93) for myocardial infarction and 1.02 (95% CI 0.99-1.05) for ischemic stroke. CONCLUSIONS: We found an overall increased risk of IS and MI during the first year after cancer surgery that was attributable to events occurring during the hospitalization period. After discharge from the hospital, the overall risk of myocardial infarction was lower among the cancer surgery patients than among matched comparison subjects.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Risk of Postoperative Ischemic Stroke and Myocardial Infarction in Patients Operated for Cancer
- Date Crossref
- 13/12/2023
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Karolinska University Hospital Department of Pelvic Cancer pays non établi dans la noticeÉtablissement de santé
-
Karolinska Institutet Department of Molecular Medicine and Surgery pays non établi dans la noticeUniversité ou école supérieure
-
Stockholm South General Hospital pays non établi dans la noticeÉtablissement de santé
-
Icahn School of Medicine at Mount Sinai Department of Urology pays non établi dans la noticeUniversité ou école supérieure
-
Clinical Epidemiology Division pays non établi dans la noticeÉtablissement de santé
-
Department of Cardiology pays non établi dans la noticeInstitution
-
Institute of Environmental Medicine Division of Biostatistics pays non établi dans la noticeStructure de recherche
-
Department of Clinical Science Division of Surgery and Oncology pays non établi dans la noticeÉtablissement de santé
Department of Pelvic Cancer — Karolinska University Hospital, Department of Molecular Medicine and Surgery — Karolinska Institutet et Stockholm South General Hospital, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.