Abstract 13856: Echocardiographic Findings in Women With Ischemic Sudden Cardiac Death
Rattachement africain : fi, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Majority of sudden cardiac deaths (SCD) are caused by coronary artery disease (CAD). Many women who experience SCD do not exhibit the traditional risk factors associated with SCD, which poses challenges in terms of SCD prevention and prediction. The data of SCD in women are limited as women are often underrepresented in SCD studies. Aim: The objective of this study was to investigate sex-specific echocardiographic findings in subjects with ischemic SCD. Methods: The study group consisted of 4392 subjects with ischemic SCD (20.2 % women) derived from the FinGesture study. The cause of death was determined at medicolegal autopsy. Pre-SCD echocardiography (ECHO) reports were collected from medical records. Ventricular and atrial dimensions as well as left ventricular mass (LVM) were categorized by using widely accepted thresholds. LVM was calculated using the LVM formula (LV Mass = (0.8 * [1.04 * ((LVEDD + IVSd + PWd) 3 - LVEDD 3 )]) + 0.6)). Left ventricular ejection fraction (LVEF) was classified into four categories: normal (>55 %), mildly reduced (45-55 %), moderately reduced (35-45 %) and severely reduced (<35 %). ECHO reports were available for 325 SCD victims (20.3 % women). Results: Left ventricular hypertrophy (LVH) was prevalent in 84.6 % of women and 76.4 % of men (p = 0.440). A thickened interventricular septum was observed in the majority of subjects in both sexes (84.8 % in women vs. 85.9 % in men, p = 1.000). Similarly, an enlarged left atrium was commonly found in both women (70.2 %) and men (72.3 %) (p = 0.856). The prevalence of dilated left ventricular end-diastolic diameter was 27.3 % in women and 30.1 % in men (p = 0.651). Overall, no significant differences were observed between the sexes in sex-adjusted ventricular or atrial dimensions. However, women with ischemic SCD were more likely to have a normal LVEF compared to men (63.4 % in women vs. 45.5 % in men, p <0.001). Additionally, the prevalence of severely reduced LVEF was significantly lower in women than in men (5.4 % in women vs. 15.9 % in men, p = 0.005). Conclusions: LVH is a common finding in subjects with ischemic SCD. Women with ischemic SCD are less likely than men to have severely reduced LVEF prior to SCD. Additionally, in women, ischemic SCD tends to occur more often without a decrease in LVEF.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Abstract 13856: Echocardiographic Findings in Women With Ischemic Sudden Cardiac Death
- Date Crossref
- 07/11/2023
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Oulu Deaconess Institute pays non établi dans la noticeÉtablissement de santé
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Cedars-Sinai Medical Center pays non établi dans la noticeÉtablissement de santé
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University of Oulu pays non établi dans la noticeUniversité ou école supérieure
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Med Rsch Cntr Oulu pays non établi dans la noticeInstitution
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Med Rsch Cntr of Oulu pays non établi dans la noticeInstitution
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Cedars-Sinai Med Cntr pays non établi dans la noticeInstitution
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Juha Vahatalo Oulu pays non établi dans la noticeInstitution
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Univ of Oulu pays non établi dans la noticeUniversité ou école supérieure
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Finnish Institute for Health and We pays non établi dans la noticeStructure de recherche
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Oulu Univ Hosp pays non établi dans la noticeUniversité ou école supérieure
Oulu Deaconess Institute, Cedars-Sinai Medical Center et University of Oulu, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.