CT coronary artery calcification score as a prognostic marker in COVID-19
Rattachement africain : de. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Coronary artery calcification (CA) score has been established as a quantitative imaging biomarker to reflect arteriosclerosis and general vessel status. It is established as an important prognostic factor for coronary heart disease but also for other disease entities. Our aim was to use this imaging marker derived from computed tomography (CT) images to elucidate the prognostic relevance in patients with coronavirus disease 2019 (COVID-19). Methods: The clinical database was retrospectively screened for patients with COVID-19 between 2020 and 2022. A total of 241 patients (85 female patients, 35.3%) were included into the analysis. CA scoring was performed semiquantitatively on thoracic CT images with the established Weston score. Results: Overall, 61 patients (25.3%) of the investigated patient sample died. In survivors, the mean CA score was 2.3±3.0 and in non-survivors, it was 4.2±4.1 (P=0.002). In univariable regression analysis, CA was associated with 30-day mortality [odds ratio (OR) =1.15; 95% confidence interval (CI): 1.06-1.25, P<0.001]. These results were confirmed by the multivariable regression analysis adjusted for age and sex, the CA score predicted 30-day mortality (OR =1.28; 95% CI: 1.08-1.4, P=0.002). Conclusions: CA score is an independent risk factor in COVID-19. As CA scoring can easily be performed by the radiologist, it should be further investigated as an imaging marker in patients with COVID-19 and potentially be translated into clinical routine.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- CT coronary artery calcification score as a prognostic marker in COVID-19
- Date Crossref
- 01/10/2023
- Éditeur
- AME Publishing Company
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Leipzig University pays non établi dans la noticeUniversité ou école supérieure
-
Otto-von-Guericke-Universität Magdeburg pays non établi dans la noticeUniversité ou école supérieure
-
Johannes Wesling Klinikum Minden pays non établi dans la noticeÉtablissement de santé
-
Ruhr University Bochum Department of Radiology pays non établi dans la noticeUniversité ou école supérieure
-
University of Leipzig Department of Diagnostic and Interventional Radiology pays non établi dans la noticeUniversité ou école supérieure
-
Otto von Guericke University Department of Radiology and Nuclear Medicine pays non établi dans la noticeUniversité ou école supérieure
Leipzig University, Otto-von-Guericke-Universität Magdeburg et Johannes Wesling Klinikum Minden, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.