Accès ouvert déclaré
2023
article
Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease
Richard A. Bernstein, Hooman Kamel, Christopher B. Granger, Jonathan P. Piccini, Jeffrey M. Katz, Pramod Sethi, Erika Pouliot, Noreli Franco, Paul Ziegler, Lee H. Schwamm, Indrani Acosta, Pradipkumar Jamnadas, Sushma Manda, Rizwan Alimohammad, Valerie Arias, Kristi Tempro, Kathleen Ward, Khaled Asi, Indrajit Choudhuri, Waldo R. Guerrero, Junaid Kalia, Imran Khan Niazi, Rehan Sajjad, Varoon Thavapalan, Manish D. Assar, Javier E. Banchs, James Black, Peter Y. K. Cheung, Alan Donsky, Dion Graybeal, Rashedul Hasan, Osman Mir, Claude Nguyen, Gregory Olsovsky, Jennifer Rasmussen, Sanjeev Hasabnis, Russell A. Reeves, Chris Rowley, Jitendra Sharma, Macey Smith, Kay Bonyak, Matthew C. Sackett, James Allred, Richard Jung, Jennifer Lynch, Steven P. Rowe, Subasini Dash, Taya V. Glotzer, Sameer Jamal, Glauco Radoslovich, Gunjan Shukla, John Zimmerman, Haitham M. Hussein, Dennis W.X. Zhu, Kristopher Krueger, Matthew Ostrander, Darwin Ramirez, Jeffrey W. Shultz, Jay Simonson, Brett Cucchiara, Rajat Deo, David S. Frankel, Judy Jia, Scott E. Kasner, Jeanie Luciano, Steven R. Messé, Michael T. Mullen, Pasquale Santangeli, Robert D. Schaller, Qingyang Yuan, Don Bledsoe, Christian Cajavilca, David Chiu, Rajan Gadhia, Maranda Randi Grimes, Larry Katz, Stacy Moye, Tapan G. Rami, John Volpi, Ali Al Balushi, Clara Boyd, Subbarao Choudry, Mandip S. Dhamoon, Srinivas R. Dukkipati, Davida Goltz, Qing Hao, Deborah Horowitz, Gurmeen Kaur, Jacob S. Koruth, Christeena Kurian, Marie-Noelle S. Langan, Iván Díaz, Marc L. Miller, Vivek Y. Reddy, Kara Sheinart, Laura Stein, Aaron Tansy, Stanley Tuhrim, Jesse Weinberger, William Whang, Jonathan Cross, Howard Kreger, Marc Saltzman, Kenneth Zide, Sandeep Bansal, Matthew A. Bernabei, Murray Flaster, Conor D. Barrett, Mark R. Etherton, E. Kevin Heist, Steven A. Lubitz, Robert W. Regenhardt, Richa Sharma, Scott Silverman, Kelly L. Sloane, Anand Viswanathan, Amit Doshi, William Logan, Maheen Malik, David A. Rempe, Rohan Arora, Stuart Beldner, Laurence M. Epstein, Haisam Ismail, Ram Jadonath, Richard Libman, Mohammad Moussavi, Anand Patel, Apoor Patel, Jonathan Willner, Paul Wright, Frances Caprio, Hanna Kim, Scott D. Mendelson, Rod Passman, Ilana Ruff, Mohammad Alsorogi, Gauhar Chaudhary, Kent Morris, Savannah Mullins, Nadeem Talpur, Breehan Chancellor, Larry A. Chinitz, Andre Culpepper, Michael Fara, Koto Ishida, Kaitlyn Lillemoe, Aaron Lord, Jose Torres, Cen Zhang, Freddy Abi‐Samra, Michael L. Bernard, Jacqueline Carter, Himanshu Chokhawala, Amanda E. Downey, Samuel Khatib, Daniel P. Morin, Glenn M. Polin, Paul Rogers, Gabriel Vidal, Richard M. Zweifler, Gary Belt, Robert A. Felberg, Steve Furer, John Hanna, Angela McCall-Brown, Susan Seeger, Ramakota Reddy, Elaine Skalabrin, Diane Soik, Michael J Wilder, Michelle Kearney, Eugene LaFranchise, Brett Parker, Robert A. Pickett, Heather Bonaguidi, Douglas Gibson, Mary Kalafut, Beth Mattera, Nicholas Olson, Mary Ann Parker, John Rogers, Poulina Q. Uddin, Cherylee W. J. Chang, Sarah Graner, Joseph Kipta, Rony Salem, David J. Singh, Ahmad Al‐Awwad, Bahar Beaver, Shuchi Chaudhary, Stephen Clayton, Claire Delpirou Nouh, Paul Garabelli, David Gordon, Aneesh Pakala, Bappaditya Ray, Scott Saucedo, Evgeny Sidorov, Stavros Stavrakis, Marilou Ching, Christopher Deline, J. Maurice Hourihane, Amit Kandel, Chee Kim, Rakesh Magun, Ashkan Mowla, Robert G. Sawyer, Donald Switzer, Nitish Badhwar, Randall Lee, Karl Meisel, Wade S. Smith, Moayd Alkahalifah, Sushanth Aroor, Negar Asdaghi, Nirav Bhatt, Víctor J. Del Brutto, George Dillon, Paul Gadient, Sebastian Koch, Litsa K. Lambrakos, Amer Malik, Erika Marulanda, Zeeshan Memon, Iván Mendoza, Raul D. Mitrani, Gustavo Ortiz, Jose Ramano, Nicole B. Sur, L. M. Torres, James M. Daniels, Mark R. Johnson, Alejandro Magadán, Ty Shang, Nancy Mcclelland, Theodore Merriam, Karah Neisen
43Citations signalées, ce qui n’est pas une note de qualité
10Institutions déclarées
2Pays d’affiliation déclarés
Rattachement africain : us, gb.
Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Importance: The STROKE AF study found that in patients with prior ischemic stroke attributed to large-artery atherosclerotic disease (LAD) or small-vessel occlusive disease (SVD), 12% developed AF over 1 year when monitored with an insertable cardiac monitor (ICM). The occurrence over subsequent years is unknown. Objectives: To compare the rates of AF detection through 3 years of follow-up between an ICM vs site-specific usual care in patients with prior ischemic stroke attributed to LAD or SVD. Design, Setting, and Participants: This multicenter, randomized (1:1) clinical trial took place at 33 sites in the US with enrollment between April 2016 and July 2019 and 3-year follow-up through July 2022. Eligible patients were aged 60 years or older, or aged 50 to 59 years with at least 1 additional stroke risk factor and had an index ischemic stroke attributed to LAD or SVD within 10 days prior to ICM insertion. Of the 496 patients enrolled, 492 were randomized and 4 were excluded. Interventions: ICM monitoring vs site-specific usual care. Main Outcomes and Measures: The prespecified long-term outcome of the trial was AF detection through study follow-up (up to 3 years). AF was defined as an episode lasting more than 30 seconds, adjudicated by an expert committee. Results: In total, 492 patients were randomized and included in the analyses (median [IQR] age, 66 [60-74] years; 307 men [62.4%] and 185 women [37.6%]), of whom 314 completed 3-year follow-up (63.8%). The incidence rate of AF at 3 years was 21.7% (46 patients) in the ICM group vs 2.4% (5 patients) in the control group (hazard ratio, 10.0; 95% CI, 4.0-25.2; P < .001). Conclusions and Relevance: Patients with ischemic stroke attributed to LAD or SVD face an increasing risk of AF over time and most of the AF occurrences are not reliably detected by standard medical monitoring methods. One year of negative monitoring should not reassure clinicians that patients who have experienced stroke will not develop AF over the next 2 years. Trial Registration: ClinicalTrials.gov Identifier: NCT02700945.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease
- Date Crossref
- 01/12/2023
- Éditeur
- American Medical Association (AMA)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Les institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Les sujets associés
Acute Ischemic Stroke ManagementAtrial Fibrillation Management and OutcomesBlood Pressure and Hypertension Studies