Accès ouvert déclaré 2023 preprint

Usability of three blood-based HIV self-testing devices among men who have sex with men and female sex workers in Yaounde and Douala, Cameroon

Awono Noah JP Yves, Justin Ndié, Francis Atéba Ndongo, Onesimus Yongwa, Rogacien Kana, Martial Gaël Bonyohe, Hedgar Plessy Mboussam, Tatiana Palisson Avang, Fatima Moulioum, Félicité Tabala Naah, Gutenberg Tchikangni, Audrey Djomo Nzaddi, Alice Ketchaji, Carelle Djofang Yepndo, Gildas Nguemkam, Charles Baudelaire Ndindjock, Brice Seukam, Yagaï Bouba, Ernest Désiré Mvilongo Anaba, Rina Estelle Djoukwe, Serge Clotaire Billong, Karin Hatzold, Annie Michele Salla, Jérôme Ateudjieu, Anne Cecile Bissek

0Citations signalées, ce qui n’est pas une note de qualité

4Institutions déclarées

1Pays d’affiliation déclarés

Rattachement africain : Cameroun. Niveau de preuve : code pays fourni par la source.

Le résumé fourni par la source

Abstract Background Blood-based HIV self-testing represents an alternative for increasing screening among key populations or populations with difficult access. In Cameroon, very few studies, on the usability of HIV self-tests based on blood samples, have been carried out among these groups. Objective The aim of this study was to assess the usability of blood-based HIV self-testing among men who have sex with men (MSM) and female sex workers (FSWs) in the cities of Yaoundé and Douala, Cameroon. Materials and Methods An observational study was conducted in 17 Community-Based Organisations (CBOs), including 10 MSM and 07 FSWs in Yaoundé and Douala from 11 to 22 June 2022. The study population consisted of HCV and MSM aged 21 years and over who agreed to participate in the study. After they were recruited consecutively in their respective CBOs, they received counselling, unassisted HIV blood self-testing and condoms. Data was collected using an administered questionnaire. Three HIV blood self-testing devices were used in the study: Mylan HIV Self-Test, Sure Check HIV Test® (Chembio Diagnostics Inc), Check Now HIV Self-Test(Abbott™ Point Of Care). Analysis was conducted using SPSS 23 software with a 95% confidence level. Results Of 817 participants who completed the HIV blood self-test, just over half were TS 459(56.2%); the median age was 27 years (IQR: 22 years - 34 years) and the 25-49 age group was most represented 482(59.0%). One participant in ten (10%) had never been tested for HIV. However, 98.6% of participants agreed to use the HIV blood self-test and the vast majority (97.1%) followed the steps for carrying out the HIV blood self-test. An MSM was 4 times more likely to pass an HIV blood self-test than a TS (aOR= 4.01; 95% CI: 1.181-13.625; p=0.026). Similarly, TS and MSM who used the Abbott Check Now HIV Self-Test (aOR= 3.85; 95% CI: 1.246-11.908; p=0.019) and Chembio Sure Check HIV Test (aOR= 2.83; 95% CI: 1.072-7.720; p=0.036) were respectively 3.8 and 2.8 times and more likely to pass their self-test than those who used the Mylan blood self-test. Agreement between a participant’s HIV blood self-test result and Abbott-trained investigator-observers was moderate (κ=0.485; CI95% (0.359-0.610); p=0.001) while agreement with Chembio and Mylan was respectively low (κ=0.329; CI95% (0.203-0.454); p=0.001) and very low (κ=0.194; CI95%(0.05-0.329); p=0.001). Conclusion HIV blood self-testing is acceptable and usable by key populations in Cameroon. Although usability was limited by problems in interpreting results and incorrect disposal of waste t by key populations, a blood-based HIV Self-Test, with moderate concordance, proved suitable for unassisted use in key populations, what could help improve HIV prevention interventions.

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Le contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref: Usability of three blood-based HIV self-testing devices among men who have sex with men and female sex workers in Yaounde and Douala, Cameroon
Date Crossref: 26/10/2023
Éditeur: openRxiv
Type: posted-content

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.

Où se fait cette recherche

Ministry of Public Health Department of Disease Control Cameroun (code pays fourni par la source)
Organisme public
Université de Garoua Université de Garoua, Cameroun (code pays fourni par la source)
Université ou école supérieure
Université de Yaoundé I Université de Yaoundé I, Cameroun (code pays fourni par la source)
Université ou école supérieure
Université de Dschang Université de Dschang, Cameroun (code pays fourni par la source)
Université ou école supérieure
Media Convergence Health Research Centre Cameroun (pays nommé en fin d’affiliation)
Structure de recherche
Faculty of Medicine University of Garoua, Cameroun (pays nommé en fin d’affiliation)
Université ou école supérieure
Cameroon Social Marketing Association Cameroun (pays nommé en fin d’affiliation)
Organisation à but non lucratif
Central Technical Group/National AIDS Control Committee pays non établi dans la notice
Institution
University of Yaounde I University of Yaounde I, Cameroun (pays nommé en fin d’affiliation)
Université ou école supérieure
Population Services International pays non établi dans la notice
Institution
University of Dschang Department of Public Health University of Dschang, Cameroun (pays nommé en fin d’affiliation)
Université ou école supérieure

Department of Disease Control — Ministry of Public Health (Cameroun), Université de Garoua (Université de Garoua, Cameroun) et Université de Yaoundé I (Université de Yaoundé I, Cameroun), avec 8 autres affiliations. Pays d’affiliation : Cameroun.

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Les sujets associés

HIV Research and TreatmentHIV/AIDS Research and InterventionsHIV, Drug Use, Sexual Risk

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