Intranasal dexmedetomidine as premedication for magnetic resonance imaging examinations in dogs with neurological disorders mitigates hypotension and hypothermia
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Le résumé fourni par la source
OBJECTIVE: This study aimed to evaluate the safety and feasibility of intranasal administration of dexmedetomidine as a premedication for preventing hypotension and hypothermia in canine patients undergoing MRI examinations. ANIMALS: Dogs undergoing MRI examinations for neurological disorders were enrolled in this study. The dogs were randomly assigned: 15 to the N-Dex group (without premedication) and 13 to the Dex group (125 μg/m2 of dexmedetomidine, intranasally, as a premedication). METHODS: During the examination, pulse rate, systolic blood pressure, diastolic blood pressure, and mean arterial blood pressure were recorded every 5 minutes for the first 30 minutes. Body temperature was measured before and after the examination. Any adverse events during the procedure were documented. RESULTS: Significant changes in pulse rate during the examination were not distinguishable. Although blood pressure and body temperature decreased in both groups under anesthesia, dogs in the Dex group had a significantly smaller drop in blood pressure and body temperature and fewer hypotension events than those in the N-Dex group MRI examinations of 1 hour's duration. Two dogs in the Dex group exhibited bradycardia at 45 and 60 minutes of MRI examination, which resolved after receiving atipamezole. CLINICAL RELEVANCE: Our results indicate that intranasal administration of 125 μg/m2 of dexmedetomidine as premedication is safe and can potentially mitigate hypothermia and hypotension in dogs with neurological disorders during MRI examinations.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Intranasal dexmedetomidine as premedication for magnetic resonance imaging examinations in dogs with neurological disorders mitigates hypotension and hypothermia
- Date Crossref
- 01/02/2024
- Éditeur
- American Veterinary Medical Association (AVMA)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Pingtung University of Science and Technology Veterinary Medical Teaching Hospital pays non établi dans la noticeUniversité ou école supérieure
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Kaohsiung Medical University pays non établi dans la noticeUniversité ou école supérieure
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National Taiwan University Hospital pays non établi dans la noticeÉtablissement de santé
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Pingtung Hospital pays non établi dans la noticeÉtablissement de santé
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College of Health Sciences Department of Medical Imaging and Radiological Sciences pays non établi dans la noticeUniversité ou école supérieure
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College of Veterinary Medicine Department of Veterinary Medicine pays non établi dans la noticeUniversité ou école supérieure
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School of Dentistry pays non établi dans la noticeUniversité ou école supérieure
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UniCore Animal Hospital pays non établi dans la noticeÉtablissement de santé
Veterinary Medical Teaching Hospital — National Pingtung University of Science and Technology, Kaohsiung Medical University et National Taiwan University Hospital, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.