APPLICATION OF AUTOLOGICAL MICROFRAGMENTED ADIPOSE TISSUE IN THE TREATMENT OF POST-RADIATION ULCERATIVE PROCTITIS
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Le résumé fourni par la source
Introduction. Post-radiation ulcerative proctitis is a serious complication after radiotherapy for cancer of the prostate, cervix and uterine body, anal canal, and other pelvic tumors. Given the mechanism of occurrence, there are currently no pathogenetic methods for the treatment of post-radiation ulcerative proctitis. Aim. Is to develop a technique and evaluate its effectiveness in the treatment of patients with post-radiation rectal ulcers using autologous microfragmented adipose tissue. Material and methods. The study included 30 patients, of which 24 (80.0% were women and 6 (20.0%) were men. Manual lipoaspiration was used to obtain autologous adipose tissue. Then, microfragmentation was performed through transfers. The introduction of autologous concentrated adipose tissue was performed in edges of post-radiation ulcerative defect of the rectal wall under endoscopic control. Results and discussion. The duration of the manipulation from the moment of adipose tissue sampling to the end of the injection was a little more than an hour (Me = 75.0 min). No intraoperative complications were identified. One patient (3.3%) had a local recurrence of cervical cancer, and therefore the patient was excluded from the study. Control rectoscopy after 6 months in 28 (93.3%) patients showed complete epithelialization of post-radiation ulcerative defects of the rectum. Conclusion. The technique of using autologous microfragmented adipose tissue is affordable and effective in the treatment of patients with post-radiation ulcerative proctitis
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- APPLICATION OF AUTOLOGICAL MICROFRAGMENTED ADIPOSE TISSUE IN THE TREATMENT OF POST-RADIATION ULCERATIVE PROCTITIS
- Date Crossref
- 01/06/2023
- Éditeur
- Contemporary Clinical Medicine
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Moscow Clinical Scientific Center pays non établi dans la noticeStructure de recherche
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Moscow Clinical Scientific and Practical Center named after I.I. A.S. Loginov of the Moscow Healthcare Department Coloproctology Department pays non établi dans la noticeÉtablissement de santé
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Moscow Clinical Scientific and Practical Center named after I.I. A.S. Loginova of the Moscow Healthcare Department Department of Operative Endoscopy pays non établi dans la noticeÉtablissement de santé
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Moscow Clinical Scientific and Practical Center named after A.I. A.S. Loginov of the Moscow Healthcare Department Head of the Department of Endoscopy pays non établi dans la noticeÉtablissement de santé
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Московский клинический научно-практический центр им. А.С. Логинова Департа-мента здравоохранения г. Москвы» pays non établi dans la noticeInstitution
Moscow Clinical Scientific Center, Coloproctology Department — Moscow Clinical Scientific and Practical Center named after I.I. A.S. Loginov of the Moscow Healthcare Department et Department of Operative Endoscopy — Moscow Clinical Scientific and Practical Center named after I.I. A.S. Loginova of the Moscow Healthcare Department, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.