Accès ouvert déclaré
2023
article
Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort
Nicolás Casco, Alberto Levi Jorge, Domingo Palmero, Jan‐Willem C. Alffenaar, Greg J. Fox, Wafaa Ezz, Jin‐Gun Cho, Justin T. Denholm, Alena Skrahina, Varvara Solodovnikova, Marcos Abdo Arbex, Tatiana Alves, Marcelo Fouad Rabahi, Giovana Rodrigues Pereira, Roberta Sales, Denise Rossato Silva, Muntasir Saffie, Nadia Escobar Salinas, Ruth Caamaño Miranda, Catalina Cisterna, Clorinda Concha, Israel Fernandez, Claudia Villalón, Carolina Guajardo Vera, Patricia Gallegos Tapia, Viviana Cancino, Monica Carbonell, Arturo Jiménez Cruz, Eduardo Muñóz, Camila Muñoz, Indira Navarro, Rolando Pizarro, Gloria Pereira Cristina Sánchez, Maria Soledad Vergara Riquelme, Evelyn Vilca, Aline Soto, Ximena Figueroa Flores, Ana Garavagno, Martina Hartwig Bahamondes, L. Merino, Ana María Pradenas, Macarena Espinoza Revillot, Patricia Rodríguez, Angeles Serrano Salinas, Carolina Taiba, Joaquín Farías Valdés, Jorge Navarro Subiabre, Carlos Ortega, Sofia Palma, Patricia Perez Castillo, Mónica Pinto, Francisco Rivas Bidegain, Margarita Venegas, Edith Yucra, Yang Li, Andres Cruz, Beatriz Guelvez, Regina Victoria Plaza, Kelly Yoana Tello Hoyos, José Landivar, Martin van den Boom, Claire Andréjak, F.–X. Blanc, Samir Dourmane, Antoine Froissart, A. Izadifar, F. Rivière, F. Schlemmer, Κaterina Manika, Boubacar Diallo, Souleymane Hassane-Harouna, Norma Artiles, Licenciada Andrea Mejia, Nitesh Gupta, Pranav Ish, Gyanshankar Mishra, Jigneshkumar M. Patel, Rupak Singla, Zarir Udwadia, Francesca Alladio, Fabio Angeli, Andrea Calcagno, Rosella Centis, Luigi Ruffo Codecasa, Angelo De Lauretis, Susanna Esposito, Beatrice Formenti, Alberto Gaviraghi, Vania Giacomet, Delia Goletti, Gina Gualano, Alberto Matteelli, Giovanni Battista Migliori, Ilaria Motta, Fabrizio Palmieri, Emanuele Pontali, Tullio Prestileo, Niccolò Riccardi, Laura Saderi, Matteo Saporiti, Giovanni Sotgiu, Antonio Spanevello, Claudia Stochino, Marina Tadolini, Alessandro Torre, Simone Villa, Dina Visca, Xhevat Kurhasani, Mohammed Furjani, Najia Rasheed, Edvardas Danila, Saulius Diktanas, Ruy López‐Ridaura, Fátima Leticia Luna López, Marcela Muñoz Torrico, Adrián Rendón, Onno W. Akkerman, Seif Al-Abri, Fatma Alyaquobi, Khalsa Al-Thohli, Sarita Aguirre, Rosarito Coronel Teixeira, Viviana de Egea, Sandra Irala, Angélica Medina, Guillermo Sequera, Natalia Sosa, Fátima Vázquez, Félix Llanos-Tejada, Selene Manga, Renzo Villanueva-Villegas, David Araújo, Raquel DuarteTânia Sales Marques, Adriana Socaci, O.N. Barkanova, Maria Bogorodskaya, Sergey M. Borisov, Andrei Mariandyshev, Anna Kaluzhenina, Tatjana Adzić Vukicevic, Maja Stošić, Darius Beh, Deborah HL Ng, Ong C, Ivan Solovič, Keertan Dheda, Phindile Gina, José A. Caminero, María Luiza de Souza-Galvão, Ángel Domínguez-Castellano, José-María García-García, Israel Molina Pinargote, Sarai Quirós Fernandez, Adrián Sánchez‐Montalvá, Eva Tabernero Huguet, Miguel Zabaleta Murguiondo, Pierre‐Alexandre Bart, Jesica Mazza‐Stalder, Lia D’Ambrosio, Phalin Kamolwat, Freya Bakko, James Barnacle, Sophie Bird, Annabel Brown, Shruthi Chandran, Kieran Killington, Kathy Man, Padmasayee Papineni, Flora Ritchie, Simon Tiberi, Natasa Utjesanovic, Dominik Zenner, Jasie Hearn, Scott K. Heysell, Laura Young
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Résumé fourni par la source
BACKGROUND: Longitudinal cohort data of patients with tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are lacking. In our global study, we describe long-term outcomes of patients affected by TB and COVID-19. METHODS: We collected data from 174 centres in 31 countries on all patients affected by COVID-19 and TB between 1 March 2020 and 30 September 2022. Patients were followed-up until cure, death or end of cohort time. All patients had TB and COVID-19; for analysis purposes, deaths were attributed to TB, COVID-19 or both. Survival analysis was performed using Cox proportional risk-regression models, and the log-rank test was used to compare survival and mortality attributed to TB, COVID-19 or both. RESULTS: those dying because of either TB or COVID-19 alone (p<0.001). Significant adjusted risk factors for TB mortality were higher age (hazard ratio (HR) 1.05, 95% CI 1.03-1.07), HIV infection (HR 2.29, 95% CI 1.02-5.16) and invasive ventilation (HR 4.28, 95% CI 2.34-7.83). For COVID-19 mortality, the adjusted risks were higher age (HR 1.03, 95% CI 1.02-1.04), male sex (HR 2.21, 95% CI 1.24-3.91), oxygen requirement (HR 7.93, 95% CI 3.44-18.26) and invasive ventilation (HR 2.19, 95% CI 1.36-3.53). CONCLUSIONS: In our global cohort, death was the outcome in >10% of patients with TB and COVID-19. A range of demographic and clinical predictors are associated with adverse outcomes.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort
- Date Crossref
- 12/10/2023
- Éditeur
- European Respiratory Society (ERS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Sujets associés
Tuberculosis Research and EpidemiologyCOVID-19 Clinical Research StudiesImmune responses and vaccinations