Fifteen Years of Iodine Prophylaxis in Italy: Results of a Nationwide Surveillance (Period 2015-2019)
Rattachement africain : it. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
CONTEXT: In 2005, a nationwide program of iodine prophylaxis on a voluntary basis was implemented in Italy by law. However, recent data on iodine status are lacking. OBJECTIVE: The aim of this study was to evaluate efficiency, effectiveness, and possible adverse effects (increased occurrence of thyroid autoimmunity and hyperthyroidism) of the Italian iodine prophylaxis program. METHODS: From 2015 to 2019, a nationwide survey was performed. The use of iodized salt was evaluated in a sample of 164 593 adults and in 998 school canteens. A sample of 4233 schoolchildren (aged 11-13 years) was recruited to assess urinary iodine concentration, prevalence of goiter, and thyroid hypoechogenicity on ultrasound, with the latter being an indirect indicator of thyroid autoimmunity. Neonatal TSH values of 197 677 infants screened in regions representative of Northern, Central, and Southern Italy were analyzed to investigate the percentage of TSH values >5.0 mIU/L. Data on methimazole prescriptions were analyzed as indirect indicators of new cases of hyperthyroidism. RESULTS: The prevalence of the use of iodized salt was 71.5% in adult population and 78% in school canteens. A median urinary iodine concentration of 124 μg/L, a prevalence of goiter of 2.2%, and a prevalence of thyroid hypoechogenicity of 5.7% were observed in schoolchildren. The percentage of neonatal TSH values >5.0 mIU/L resulted still higher (5.1%) than the World Health Organization threshold of 3.0%, whereas the prescriptions of methimazole showed a reduction of 13.5%. CONCLUSION: Fifteen years of iodine prophylaxis have led to iodine sufficiency in Italy, although there still is concern about iodine nutritional status during pregnancy.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Fifteen Years of Iodine Prophylaxis in Italy: Results of a Nationwide Surveillance (Period 2015-2019)
- Date Crossref
- 11/10/2023
- Éditeur
- The Endocrine Society
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Istituto Superiore di Sanità pays non établi dans la noticeOrganisme public
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National Centre for Disease Prevention and Control pays non établi dans la noticeOrganisme public
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University of Genoa Department of Internal Medicine and Medical Specialties pays non établi dans la noticeUniversité ou école supérieure
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University of Calabria Department of Pharmacy pays non établi dans la noticeUniversité ou école supérieure
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University of Molise Department of Medicine and Health Sciences “V. Tiberio pays non établi dans la noticeUniversité ou école supérieure
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Istituto Ramazzini pays non établi dans la noticeStructure de recherche
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University of Padua Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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University of Perugia Department of Medicine and Surgery pays non établi dans la noticeUniversité ou école supérieure
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Marche Polytechnic University pays non établi dans la noticeUniversité ou école supérieure
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University of Pisa Department of Clinical and Experimental Medicine pays non établi dans la noticeUniversité ou école supérieure
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Sapienza University of Rome pays non établi dans la noticeUniversité ou école supérieure
Istituto Superiore di Sanità, National Centre for Disease Prevention and Control et Department of Internal Medicine and Medical Specialties — University of Genoa, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.