Seroprevalence of Brucella spp. and Rift Valley fever virus among slaughterhouse workers in Isiolo County, northern Kenya
Rattachement africain : Kenya, de, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Brucella spp. and Rift Valley fever virus (RVFV) are classified as priority zoonotic agents in Kenya, based on their public health and socioeconomic impact on the country. Data on the pathogen-specific and co-exposure levels is scarce due to limited active surveillance. This study investigated seroprevalence and co-exposure of Brucella spp. and RVFV and associated risk factors among slaughterhouse workers in Isiolo County, northern Kenya. A cross-sectional serosurvey was done in all 19 slaughterhouses in Isiolo County, enrolling 378 participants into the study. The overall seroprevalences for Brucella spp. and RVFV were 40.2% (95% CI: 35.2-45.4) and 18.3% (95% CI: 14.5-22.5), respectively while 10.3% (95% CI 7.4%-13.8%) of individuals were positive for antibodies against both Brucella spp. and RVFV. Virus neutralisation tests (VNT) confirmed anti-RVFV antibodies in 85% of ELISA-positive samples. Our seroprevalence results were comparable to community-level seroprevalences previously reported in the area. Since most of the study participants were not from livestock-keeping households, our findings attribute most of the detected infections to occupational exposure. The high exposure levels indicate slaughterhouse workers are the most at-risk population and there is need for infection, prevention, and control programs among this high-risk group. This is the first VNT confirmation of virus-neutralising antibodies among slaughterhouse workers in Isiolo County and corroborates reports of the area being a high-risk RVFV area as occasioned by previously reported outbreaks. This necessitates sensitization campaigns to enhance awareness of the risks involved and appropriate mitigation measures.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Seroprevalence of Brucella spp. and Rift Valley fever virus among slaughterhouse workers in Isiolo County, northern Kenya
- Date Crossref
- 05/10/2023
- Éditeur
- Public Library of Science (PLoS)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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International Livestock Research Institute Nairobi, Kenya (code pays fourni par la source)Structure de recherche
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Ministry of Agriculture Livestock and Fisheries Kenya (code pays fourni par la source)Organisme public
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Ministry of Health Kenya Zoonotic Disease Unit Nairobi, Kenya (code pays fourni par la source)Organisme public
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University of Embu Department of Biological Sciences Kenya (code pays fourni par la source)Université ou école supérieure
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Freie Universität Berlin pays non établi dans la noticeUniversité ou école supérieure
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Los Alamos National Laboratory Genomics and Bioanalytic pays non établi dans la noticeStructure de recherche
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Dahlem Research School of Biomedical Sciences (DRS) Department of Veterinary Medicine pays non établi dans la noticeUniversité ou école supérieure
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World Organization for Animal Health Nairobi, Kenya (pays nommé en fin d’affiliation)Institution
International Livestock Research Institute (Nairobi, Kenya), Ministry of Agriculture Livestock and Fisheries (Kenya) et Kenya Zoonotic Disease Unit — Ministry of Health (Nairobi, Kenya), avec 5 autres affiliations. Pays d’affiliation : Kenya.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.