Validity of Clinical Severity Scores for Respiratory Syncytial Virus: A Systematic Review
Rattachement africain : gb, cn, be, us, nl, Afrique du Sud. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Respiratory syncytial virus (RSV) is a widespread respiratory pathogen, and RSV-related acute lower respiratory tract infections are the most common cause of respiratory hospitalization in children <2 years of age. Over the last 2 decades, a number of severity scores have been proposed to quantify disease severity for RSV in children, yet there remains no overall consensus on the most clinically useful score. METHODS: We conducted a systematic review of English-language publications in peer-reviewed journals published since January 2000 assessing the validity of severity scores for children (≤24 months of age) with RSV and/or bronchiolitis, and identified the most promising scores. For included articles, (1) validity data were extracted, (2) quality of reporting was assessed using the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis checklist (TRIPOD), and (3) quality was assessed using the Prediction Model Risk Of Bias Assessment Tool (PROBAST). To guide the assessment of the validity data, standardized cutoffs were employed, and an explicit definition of what we required to determine a score was sufficiently validated. RESULTS: Our searches identified 8541 results, of which 1779 were excluded as duplicates. After title and abstract screening, 6670 references were excluded. Following full-text screening and snowballing, 32 articles, including 31 scores, were included. The most frequently assessed scores were the modified Tal score and the Wang Bronchiolitis Severity Score; none of the scores were found to be sufficiently validated according to our definition. The reporting and/or design of all the included studies was poor. The best validated score was the Bronchiolitis Score of Sant Joan de Déu, and a number of other promising scores were identified. CONCLUSIONS: No scores were found to be sufficiently validated. Further work is warranted to validate the existing scores, ideally in much larger datasets.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Validity of Clinical Severity Scores for Respiratory Syncytial Virus: A Systematic Review
- Date Crossref
- 05/10/2023
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Edinburgh College pays non établi dans la noticeUniversité ou école supérieure
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Medical Research Scotland pays non établi dans la noticeOrganisation à but non lucratif
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University of Edinburgh pays non établi dans la noticeUniversité ou école supérieure
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Nanjing Medical University pays non établi dans la noticeUniversité ou école supérieure
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GlaxoSmithKline (Belgium) pays non établi dans la noticeEntreprise
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GlaxoSmithKline (United States) pays non établi dans la noticeEntreprise
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University Medical Center Utrecht Department of Pediatrics pays non établi dans la noticeÉtablissement de santé
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University of the Witwatersrand University of the Witwatersrand, Afrique du Sud (code pays fourni par la source)Université ou école supérieure
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Agincourt Health and Socio-Demographic Surveillance System Afrique du Sud (code pays fourni par la source)Institution
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College of Medicine and Veterinary Medicine Edinburgh Medical School pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt) University of the Witwatersrand, Afrique du Sud (pays nommé en fin d’affiliation)Université ou école supérieure
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Epidemiology Viral Non-respiratory VaccinesValue Evidence and Outcomes pays non établi dans la noticeInstitution
Edinburgh College, Medical Research Scotland et University of Edinburgh, avec 9 autres affiliations. Pays d’affiliation : Afrique du Sud.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.