Relationships Of Lumbar Spine Trabecular Bone Score And Bone Mineral Density In Older Women

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It is well known that postmenopausal women are more predisposed to osteopenia and osteoporosis due to estrogen deficiency. Although bone mineral density (BMD) measured by dual energy x-ray absorptiometry (DXA) is a major determinant of bone strength, many other factors contribute to the risk of fractures. Trabecular Bone Score (TBS) is a novel method to estimate the trabecular microarchitecture using the lumbar spine DXA image, which can potentially evaluate bone health at an earlier stage (Silva et al. 2014). PURPOSE: To examine the relationships between the lumbar spine TBS and BMD in postmenopausal women. METHODS: Twenty-three female participants aged 50 to 77 years old completed the study (Age 59.4 ± 7.4 years old; Height 163.6 ± 6.1 cm; Weight 71.6 ± 11.9 kg). Total body composition and BMD at the lumbar spine and dual proximal femur were measured by DXA. Osteopenia (-2.5 < BMD T-score ≤ -1) and osteoporosis (BMD T-score ≤ -2.5) were classified according to the WHO criteria. Pearson’s correlation coefficient was used to explore the relationships between TBS and bone variables. RESULTS: Based on BMD T-score, the prevalence of osteopenia and osteoporosis of this group of participants was 47.82% (11 out of 23 participants). The lumbar spine TBS moderately correlated with lumbar spine and total hip BMD and total bone mass (Table 1). No significant correlations were found between TBS and age, height, and weight. CONCLUSION: Trabecular bone score could be complementary to standard BMD measurements to evaluate bone health and fracture risks. Table 1. Correlations of Lumbar Spine TBS and Bone Variables (n = 23) - Variables R Value P value L1 – L4 BMD 0.543 0.007 Left Total Hip BMD 0.587 0.003 Right Total Hip BMD 0.604 0.002 Total Bone Mass 0.590 0.003

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