Findings on High Resolution Computed Tomography in Symptomatic Veterans with Deployment-Related Lung Disease
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Le résumé fourni par la source
PURPOSE: Military deployment to dusty, austere environments in Southwest Asia and Afghanistan is associated with symptomatic airways diseases including asthma and bronchiolitis. The utility of chest high-resolution computed tomographic (HRCT) imaging in lung disease diagnosis in this population is poorly understood. We investigated visual assessment of HRCT for identifying deployment-related lung disease compared with healthy controls. MATERIALS AND METHODS: Chest HRCT images from 46 healthy controls and 45 symptomatic deployed military personnel with clinically confirmed asthma and/or biopsy-confirmed distal lung disease were scored by 3 independent thoracic radiologists. We compared demographic and clinical characteristics and frequency of imaging findings between deployers and controls, and between deployers with asthma and those with biopsy-confirmed distal lung disease, using χ 2 , Fisher exact or t tests, and logistic regression where appropriate. We also analyzed inter-rater agreement for imaging findings. RESULTS: Expiratory air trapping was the only chest CT imaging finding that was significantly more frequent in deployers compared with controls. None of the 24 deployers with biopsy-confirmed bronchiolitis and/or granulomatous pneumonitis had HRCT findings of inspiratory mosaic attenuation or centrilobular nodularity. Only 2 of 21 with biopsy-proven emphysema had emphysema on HRCT. CONCLUSIONS: Compared with surgical lung biopsy, visual assessment of HRCT showed few abnormalities in this small cohort of previously deployed symptomatic veterans with normal or near-normal spirometry.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Findings on High Resolution Computed Tomography in Symptomatic Veterans with Deployment-Related Lung Disease
- Date Crossref
- 15/09/2023
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Jewish Health pays non établi dans la noticeÉtablissement de santé
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University of Colorado Denver Department of Biostatistics and Informatics pays non établi dans la noticeUniversité ou école supérieure
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Radiology Associates pays non établi dans la noticeÉtablissement de santé
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VA Eastern Colorado Health Care System pays non établi dans la noticeÉtablissement de santé
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School of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Radiology Imaging Associates pays non établi dans la noticeInstitution
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Veterans Administration Eastern Colorado Health Care System pays non établi dans la noticeInstitution
National Jewish Health, Department of Biostatistics and Informatics — University of Colorado Denver et Radiology Associates, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.