Features of decision-making in patients with alcohol dependence

Résumé fourni par la source

Objective. To identify electroencephalographic correlates of decision—making features in patients with alcohol dependence. Material and methods. Forty men with alcohol dependence were examined as the main group. Thirty people were examined as a control group. The Cambridge Gambling Task and the Iowa Gambling Task were used to study decision—making functions. Additionally, a background electroencephalogram was recorded with the calculation of absolute spectral power indicators Results. In the main group, the relatively higher indicators of decision—making logic (65 [50; 80]%, p<0.05) were associated with larger values of the spectral power of the theta and alpha rhythm of the electroencephalogram in the central and parietal-occipital leads (R=0.426, p=0.019; R=0.418, p=0.022; R=0.394, p=0.028 and R=0.445, p=0.014; R=0.458, p=0.011; R=0.382, p=0.035, respectively). Difficulties in making decisions based on emotional learning in patients with alcohol dependence were associated with larger values of the spectral power of the beta rhythm of the electroencephalogram in the temporal leads. Conclusions. The study showed that the deficit of decision—making functions in patients with alcohol dependence may be due to an imbalance of the excitation/inhibition mechanisms in the brain.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.