Accès ouvert déclaré 2023 article

Immunogenicity of a 2-Dose Regimen of Moderna mRNA Beta/Omicron BA.1 Bivalent Variant Vaccine Boost in a Randomized Clinical Trial

Nadine Rouphael, Angela R Branche, David Diemert, Ann R. Falsey, Cecilia Losada, Lindsey R. Baden, Sharon E. Frey, Jennifer A. Whitaker, Susan J. Little, Satoshi Kamidani, Richard M. Novak, Richard Rupp, Lisa A. Jackson, Tara M Babu, Angelica C Kottkamp, Anne F. Luetkemeyer, Lilly Cheng Immergluck, Rachel M. Presti, Patricia Winokur, Siham Mahgoub, Paul Goepfert, Dahlene N. Fusco, Robert L. Atmar, Christine M. Posavad, Antonia Netzl, Kalyani Telu, Jinjian Mu, Lisa J McQuarrie, Mat Makowski, Mamodikoe Makhene, David C. Montefiori, Paul C. Roberts, John H. Beigel, Elissa Malkin, Jeffrey Bethony, Aimee Desrosiers, Marc Siegel, Edward E. Walsh, Patrick Kingsley, Michael Peasley, Daniel S. Graciaa, Hady Samaha, Paulina A. Rebolledo, Zanthia Wiley, Amy C Sherman, Stephen R. Walsh, Alexandra Tong, Rebecca Rooks, Getahun Abate, Zacharoula Oikonomopoulou, Daniel F. Hoft, Irene Graham, Hana M. El Sahly, Wendy A. Keitel, Catherine Healy, Thomas Martin, Nicole Carter, Steven Hendrickx, Evan J. Anderson, Christina A. Rostad, Etza Peters, Michael J. Smith, M. Anthony Moody, Kenneth E. Schmader, Benjamin G Ladner, Andrea Wendrow, Jessica Herrick, Laura Porterfield, Maya Dunstan, Rebecca Lau, Barbara Carste, Anna Wald, Taylor Krause, Kirsten Hauge, Mark J. Mulligan, Tamia Davis, Celia Engelson, Vijaya L Soma, Chloe Harris, Azquena Munoz Lopez, Erica Johnson, Austin Chan, Jane A. O’Halloran, Ryley M. Thompson, Andrew Fleming, Sajumon Joseph, Jeffery L. Meier, Jack T. Stapleton, Sarah Shami, Arnaud Drouin, Florice K Numbi, Kirsten E. Lyke, David S. Stephens, Kathleen M. Neuzil, Monica M. Farley, Jeanne Marrazzo, Sidnee Paschal Young, Jeffery Lennox, Linda M. McNeil, Elizabeth R. Brown, Megan A Meagher, Mike Gale, Kuleni Abebe, Heather Hill, Jim Albert, Holly Baughman, Lisa McQuarrie, Teri C Lewis, Lisa Giebeig, Theresa Engel, Caleb Griffith, W L McDonald, Alissa E Burkey, Lisa Hoopengardner, Jessica E. Linton, Nikki Gettinger, Amanda Eaton, Samuel Wilks, Sina Türeli, Mohammed Elsafy, Rhonda Pikaart-Tautges, Janice Arega, Binh Hoang, Dan Curtin, Hyung Il Koo, Elisa Sindall, Marciela M. DeGrace, Diane J. Post, Seema Nayak

3Citations signalées — pas une note de qualité

34Institutions déclarées

2Pays d’affiliation déclarés

Résumé fourni par la source

We compared the serologic responses of 1 dose versus 2 doses of a variant vaccine (Moderna mRNA-1273 Beta/Omicron BA.1 bivalent vaccine) in adults. A 2-dose boosting regimen with a variant vaccine did not increase the magnitude or the durability of the serological responses compared to a single variant vaccine boost.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.

Contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref: Immunogenicity of a 2-Dose Regimen of Moderna mRNA Beta/Omicron BA.1 Bivalent Variant Vaccine Boost in a Randomized Clinical Trial
Date Crossref: 10/08/2023
Éditeur: Oxford University Press (OUP)
Type: journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.

Institutions déclarées

Emory University HOPE Clinic University of Rochester George Washington University Brigham and Women's Hospital Harvard University Baylor College of Medicine Saint Louis University University of California San Diego Children's Healthcare of Atlanta Duke University University of Illinois Chicago The University of Texas Medical Branch at Galveston Kaiser Permanente Washington Health Research Institute University of Washington New York University San Francisco General Hospital University of California, San Francisco Morehouse School of Medicine Washington University in St. Louis Long Island University University of Iowa Howard University Hospital Tulane University University of Alabama at Birmingham Fred Hutch Cancer Center Clinical Research Consortium University of Cambridge Emmes (United States)National Institutes of Health National Institute of Allergy and Infectious Diseases ENT and Allergy Manhattan Psychiatric Center Infectious Disease Research Institute

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Sujets associés

SARS-CoV-2 and COVID-19 ResearchImmunotherapy and Immune ResponsesRNA Interference and Gene Delivery

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