VERDICT-MRI Analysis of False Positives in Prostate Mp-MRI

Résumé fourni par la source

Mp-MRI has moderate specificity for the diagnosis of prostate cancer, resulting in many false positive results and unnecessary biopsies for patients with other prostatic diseases. This work presents an approach using VERDICT-MRI to investigate differences in microstructural parameter estimates between normal prostate tissue, false positive lesions and clinically-significant cancer. The VERDICT intracellular volume fraction and intrinsic diffusivity in the extracellular-extravascular space can discriminate false positive lesions with greater accuracy than the clinical ADC from mp-MRI. These results show VERDICT has the potential to identify false positives and reduce unnecessary biopsies in prostate patients.

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