Recent developments on solid phase microextraction (SPME) coatings for in vivo analysis

Résumé fourni par la source

In vivo solid phase microextraction (in vivo SPME) has been regarded as a promising high-throughput sample preparation technique for bioanalysis fields in recent years due to its simplicity, great sensitivity and low invasiveness. Therefore, as the key driving force of the development of this technique, many important advances have been also made in biocompatible coating materials. In view of this, this review here focused on various types of materials that are currently popular as in vivo SPME coating for both the targeted and untargeted analysis in living system. The main performance of each exemplary material and its current application as an in vivo SPME extraction phase were summarized in detail. As was shown, the development and the improvement of coating materials make in vivo SPME display a great potential for the targeted and untargeted screening of small molecules in living organisms. Finally, it was emphasized that the implementation of in vivo SPME in the fields of bioanalysis should be more concerned as long as suitable coating materials are available.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.