The Magseed Marker in Impalpable Breast Cancer: A Single Centre Review of Efficacy and Safety

Résumé fourni par la source

Aim: A cohort observational study was conducted, aiming to review the overall efficacy and safety of the Magseed localisation technique in non-palpable breast cancer, in comparison to wire guided excisions (WGE). Methods: Data was collected in a single centre, on all patients undergoing image guided breast conserving surgery between April 2018 and August 2019, with a planned accumulation of 100 patients undergoing Magseed localisation. During the same period, data was also collected for 100 consecutive patients undergoing WGE. Primary end points observed included excision volumes and re-excision rates. Results: Re-excision rates due to positive margins were significantly higher in the WGE group (WGE 26% vs. Magseed 8%, p<0.05). Specimen sizes by weight were also larger for WGE group (WGE 50.4g vs. Magseed 31.2g p=<0.05). 41% of WGE cases were delayed (average 62mins) when compared to 0% of Magseed cases. Conclusions: The previously recognised gold standard method of WGE has documented limitations. Our study illustrates the Magseed marker as an effective alternative method of lesion localisation, which reduces re-excision rates, improves theatre scheduling, and reduces volume of excision tissue, improving overall cosmetic outcome.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.