Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial

Samuel M. Brown, Christina E. Barkauskas, Birgit Grund, Shweta Sharma, Andrew Phillips, Lindsay Leither, Ithan D. Peltan, Michael J. Lanspa, Daniel L Gilstrap, Ahmad Mourad, Kathleen Lane, Jeremy R. Beitler, Alexis Serra, Ivan Garcia, Eyad Almasri, Mohamed Fayed, Kinsley Hubel, Estelle S. Harris, Elizabeth A. Middleton, Macy A G Barrios, Kusum S. Mathews, Neha Goel, Samuel Acquah, Jarrod Mosier, Cameron Hypes, Elizabeth Salvagio Campbell, Akram Khan, Catherine L. Hough, Jennifer G. Wilson, Joseph E. Levitt, Abhijit Duggal, Siddharth Dugar, Andrew Goodwin, Charles R. Terry, Peter Chen, Sam Torbati, Nithya Iyer, Uriel Sandkovsky, Nicholas J. Johnson, Bryce R. H. Robinson, Michael A. Matthay, Neil R. Aggarwal, Ivor S. Douglas, Jonathan D. Casey, Manuel Hache-Marliere, J.G. Youssef, William Nkemdirim, Brad Leshnower, Omar Awan, Sonal Pannu, D. Shane O’Mahony, Prasad Manian, J.W. Awori Hayanga, Glenn Wortmann, Bruno Martins Tomazini, Robert F. Miller, Jens‐Ulrik Stæhr Jensen, Daniel D. Murray, Nina A. Bickell, Jigna Zatakia, Sarah Burris, Elizabeth S. Higgs, Ven Natarajan, Robin Dewar, Adam Schechner, Nayon Kang, Alejandro Arenas‐Pinto, Fleur Hudson, Adit A. Ginde, Wesley H. Self, Cathryn F. Oldmixon, Haley Morin, Adriana Sánchez, Amy Weintrob, Alexandre Biasi Cavalcanti, Anne Davis‐Karim, Nicole Engen, Eileen Denning, Bruce Thompson, Annetine C. Gelijns, Virginia L. Kan, Victoria J. Davey, Jens Lundgren, Abdel G. Babiker, James D. Neaton, H. Clifford Lane, John Tierney, Susan Vogel, Laura A. McNay, Kelly Cahill, Page Crew, Ratna Sardana, Sharo Segal Raim, Negin Atri, Mark D. Miller, David Vallée, Lucy Chung, Yvette Delph, Stacey J. Adam, Sarah Read, Ruxandra Draghia‐Akli, Rachel Harrigan, Amy Carlsen, Anita Carter, Alain DuChêne, Kate Eckroth, Alex Frase, Merrie Harrison, Sue Meger, Kien Quan, Siu Fun Quan, Cavan Reilly, Jamie Walski, Alan J. Moskowitz, Emilia Bagiella, Ellen Moquete, Karen O'Sullivan, Mary E. Marks, Evan Accardi, Emily Kinzel, Gabriela Bedoya, Lopa Gupta, Jessica Overbey, Maria L. Padillia, Milerva Santos, Marc A. Gillinov, Marissa A. Miller, Wendy C. Taddei‐Peters, Kathleen N. Fenton, Peter K. Smith, Andrew M. Vekstein, Emily R. Ko, Mashael Al‐Hegelan, Lauren M. McGowan, Mary Motta, Shauna Howell, F. R. van der Bent, Rachel Kalager, Emmanuel Chan, Heather L. Aloor, Shannon M. Griffin, Anna Covington, Beth McLendon-Arvik, Barbara Bussadori, Mary Miller-Bell, Cathy Sampey, Vincent Gaver, Beth Hollister, Dana M. Giangiacomo, Alena Pauley, Aashay Patel, Chris Classon, Madison Frazier, Robyn Osborne, Debbi H. Conlon, Mary‐Beth Joshi, Robert Gottlieb, M. Mack, Mezgebe Berhe, Clinton Haley, Emma Dishner, Christopher Bettacchi, Kevin Golden, Erin Duhaime, Madison Ryan, Catherine Tallmadge, Lorie Estrada, Felecia Jones, Samantha Villa, Samantha Wang, Raven Robert, Tanquinisha Coleman, Laura Clariday, Rebecca Baker, Mariana Hurutado-Rodriguez, Nazia Iram, Michelle Fresnedo, Allyson Davis, Kiara Leonard, Noelia Ramierez, Jon Thammavong, Krizia Duque, Emma Turner, T. L. Fisher, Dianna Robinson, Desirae Ransom, Nicholas Maldonado, Erica Lusk, Aaron Killian, Adriana Palacios, Edilia Solis, Janet Jerrow, Matthew Watts, Heather Whitacre, Elizabeth Cothran, William Bender, Jeffrey J. Miller, Katherine L. Nugent, Woodrow J. Farrington, Kim T. Baio, Mary K. McBride, Michele Fielding, Sonya Mathewson, Kristina Porte, Elizabeth Haley, Susan Rogers, Derrick Tyler, Emerson C. Perin, Briana Costello, Alexander Postalian, M. Rizwan Sohail, Punit Hinsu, Carolyn Watson, Casey Kappenman, James Chen, Kim Walker, Melyssa Fink, Kim Mahon, Lydia Sturgis, Patrick Maher, Linda Rogers, Nicole Ng, Jason Marshall, Adel Bassily‐Marcus, Ivy Cohen, Shamini Ramoo, Aryan Malhotra, Jonathan Kessler, Rebekah Goetz, Vinay Badhwar, Lisa Giblin Sutton, Roger A. Williams, Elizabeth Berry Bartolo, Dmitry Walker, Robin Bunner, Chad Glaze, Tanja Aucremanne, J.M. Bishop, Macey Kelley, Autumn Peterson, Erica Sauerborn, Robin Reckart, Brittany Miller, Aaron Mittel, Anita Darmanian, Amanda Rosen, Purnema Madahar, John Schicchi, Katarzyna Gosek, Amy Dzierba, Romina Wahab, Connie Eng, Mustafa Alsaadi, Faisal Zahiruddin, Mohi Syed, Michael George, Varsha Patel, Chisom Onwunyi, Rosa Barroso da Costa, Crystal M. North, Nancy Ringwood, Laura Fitzgerald, Ariela Muzikansky, Richard P. Morse, Roy G. Brower, Lora A. Reineck, Karen Bienstock, Peter Hou, Jay S. Steingrub, Mark Tidswell, Lori-Ann Kozikowski, Cynthia Kardos, Leslie De Souza, Daniel Talmor, Nathan I. Shapiro, Kathryn A. Hibbert, Kelsey Brait, Mamary Kone, Gregory Hendey, Kirsten N. Kangelaris, Kimia Ashktorab, Rachel Gropper, Anika Agrawal, Kelly Timothy, Hanjing Zhou, Alyssa Hughes, Rebekah Garcia, Adrián Torres, Maria Elena Hernandez-Almaraz, Rosemary Vojnik, Cynthia Pérez, Jordan H. McDowell, Steven Y. Chang, Julia Vargas, Marc Moss, Jeffrey McKeehan, Carrie Higgins, Emily L. Johnson, Suzanne Slaughter, David Wyles, Terra Hiller, Judy Oakes, Ana Garcia, Stephanie Gravitz, Carolynn Lyle, Diandra D. Swanson, Michelle N. Gong, Lynnne D. Richardson, Jen-Ting Chen, Ari Moskowitz, Amira Mohamed, Brenda López, Omowunmi Amosu, Hiwet Tzehaie, Sabah Boujid, Billie Bixby, Anitza A. Lopez, JaVon Durley, Boris Gilson, R. Duncan Hite, Henry E. Wang, Hebert P. Wiedemann, Omar Mehkri, Kiran Ashok, Alexander H. King, Connery Brennan, Matthew C. Exline, Joshua A. Englert, Sarah Karow, Elizabeth Schwartz, Preston So, Madison So, Olivia Krol, G. Parra, Emmanuel Mills, Minn Oh, José Peña, Jesús Alejandro Martínez, Susan Jackman, Emad Bayoumi, Ethan Pascual, Antonina Caudill, Po-En Chen, Tabia Richardson, Gregg J. Clapham, Lisa Herrera, Cristabelle Ojukwu, Devin Fine, Millie Gomez, Yunhee Choi-Kuaea, Gwendolyn Weissberg, Katherine Isip, Brittany Mattison, Dana Tran, Jennifer Emilov Dukov, Paul J. Chung, B Kang, Lauren Escobar, Trung N. Tran, Saba Baig, Julie A. Wallick, Alexandria M. Duven, Dakota D. Fletcher, Stephanie Gundel, Megan Fuentes, Maranda Newton, Emily Peterson, Kelsey Jiang, D. Clark Files, Chadwick Miller, Caitlin Lematty, April Rasberry, Ashley Warden, Joseph Bledsoe, Kirk U. Knowlton, Daniel Knox, Carolyn Klippel, Brent Armbruster, Darrin Applegate, Karah Imel, Melissa Fergus, Kasra Rahmati, Hannah Jensen, Valerie Aston, Joshua Jeppson, J. Hunter Marshall, Jenna Lumpkin, Cassie Smith, Tyler Burke, Andrew Gray, Robert Paine, Sean J. Callahan, Misty B. Yamane, Lindsey Waddoups, Todd W. Rice, Jakea Johnson, Christopher Gray, Margaret Hays, Megan Roth, Sarah Musick, Karen Miller, Matthew W. Semler, L. Popielski, Amy Kambo, Kimberly Viens, Melissa Turner, Michael J. Vjecha, Rachel Denyer, Rahul Khosla, Bindu Rajendran, Melissa Gonzales, Theresa Moriarty, Kousick Biswas, Cristin Harrington, Amanda Núñez García, Tammy Bremer, T. R. JUN. BURKE, Brittany Koker, David W. Pittman, Shikha Vasudeva, James D. Anholm, Lennard Specht, Aimee Rodriguez, Han Ngo, Lien Duong, Matthew Previte, Dorthe Raben, Charlotte Nielsen, Jakob Friis Larsen, Lars Peters, Gail Matthews, Anthony D. Kelleher, Mark N. Polizzotto, Catherine L. Carey, Christina C. Chang, Nila J. Dharan, Sally Hough, Sophie Virachit, Sarah Davidson, Daniel J. Bice, Katherine Ognenovska, Gesalit Cabrera, Ruth Flynn, Mazin Abdelghany, Beth Baseler, Marc Teitelbaum, H. Preston Holley, Shirley Jankelevich, Amy Adams, Nancy Becker, Suzanne Doleny, Debbie Hissey, Shelly Simpson, Mi Ha Kim, Joy Beeler, Liam Harmon, Sharon Vanderpuye, Lindsey Yeon, Leanna Frye, Erin R. Rudzinski, Molly Buehn, Vanessa Eccard-Koons, Sadie Frary, Leah MacDonalad, Jennifer Cash, Lisa Hoopengardner, Jessica Linton, Michaela Nelson, Mary Spinelli-Nadzam, Calvin Proffitt, Christopher Lee, Theresa Engel, Laura Fontaine, CK Osborne, Matt Hohn, Michael Galcik, DeeDee Thompson, Jen Sandrus, Jon Manchard, Jiwan Giri, Stacy L. Kopka, Weizhong Chang, Brad T. Sherman, Adam Rupert, Helene Highbarger, Michael Baseler, Perrine Lallemand, Tauseef Ur Rehman, Tomozumi Imamichi, Sylvain Laverdure, Sharada Paudel, Kyndal Cook, Kendra Haupt, Allison Hazen, Yunden Badralmaa, Jeroen Highbarger, Ashley L. McCormack, Norman P. Gerry, Kenneth E. Smith, Bhakti Patel, Nadia Domeraski, Marie L. Hoover, Nadine DuChateau, Adam Flosi, Rich Nelson, Jelena Stojanović, Christine Wenner