Abstract 234: Increased Likelihood Of Survival For Patients Presenting With Non-shockable Cardiac Arrest And Treated With A Device-assisted Head-up CPR Bundle
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Le résumé fourni par la source
Introduction: Despite receiving conventional (C) CPR and other standard treatments, almost all out-of-hospital cardiac arrest (OHCA) patients with non-shockable presentations will still die. As non-shockable presentations comprise nearly 80% of all OHCA cases, alternative treatment strategies are clearly indicated. Hypothesis: Compared to C-CPR controls, treatment with AHUP CPR (defined as the combination of an automated head up positioning [AHUP] device, an impedance threshold device [ITD], and manual and/or automated suction cup-based CPR), increases the probability of survival (SURV) to hospital discharge as well as neurologically favorable survival (N-SURV) for OHCA patients with (first recorded) non-shockable presentations. Methods: Prospectively collected data were obtained from a national AHUP CPR registry from 5 early adopting first responder EMS agencies that routinely initiated immediate AHUP CPR and tracked OHCA outcomes. Comparisons were made to C-CPR controls using individual patient data from high-performing prehospital systems participating in the NIH-funded Resuscitation Outcomes Consortium ROC-PRIMED and ResQTrial studies. AHUP and C-CPR patients presenting with a non-shockable rhythm were matched for the same discrete time interval from the 9-1-1 call to EMS CPR start time and propensity score for the key baseline covariables associated with outcome (e.g., age, sex, bystander-witnessed, bystander CPR) with a 1:1 ratio. Neuro-intact survival was defined as a modified Rankin Scale < 3 or Cerebral Performance Category 1 or 2. Results: AHUP CPR treatment in non-shockable rhythm cases (n=380) was associated with increased unadjusted SURV rates of 7.4% vs 3.1% for C-CPR controls (1,852): Odds ratios (OR) and 95% confidence intervals [CI] = 2.46 [1.33-3.92]. After propensity matching, AHUP CPR was associated with increased SURV and N-SURV vs C-CPR controls: OR[CI] were 2.84[1.35-5.96] and 3.87[1.27-11.78], respectively. Also, the faster AHUP was initiated, the greater the benefit. Conclusions: This analysis provides strong clinical evidence of higher likelihood of survival, including favorable neurological function, for the vast majority of OHCA patients who present with a non-shockable rhythm by using AHUP CPR.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Abstract 234: Increased Likelihood Of Survival For Patients Presenting With Non-shockable Cardiac Arrest And Treated With A Device-assisted Head-up CPR Bundle
- Date Crossref
- 08/11/2022
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
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Toledo Lucas County Public Library, Emanuel University et Allina Health, avec 9 autres affiliations.
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