Stress and polycystic ovarian syndrome-a case control study among Indian women
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Le résumé fourni par la source
Background Polycystic ovarian syndrome (PCOS) is a common hormonal disorder that women belonging to premenopausal age group encounter. Due to its increasing incidence and burden of disease, re-searching the etiopathogenesis of this syndrome is essential and the need of the hour. Recently, the role of stress in the pathogenesis of the syndrome has come into the picture. Hence this study was done to find any significant difference in stress hormone levels between PCOS and healthy controls. Methods A case-control study was conducted in SRIHER from 2019 to 2021 of which 250 participants were enrolled. Among the 250 subjects, 100 were diagnosed cases of polycystic ovarian syndrome and 150 were healthy women controls. Serum levels of DHEA and cortisol were measured using ELISA technique and the data obtained was statistically analyzed to check for significance. Results The serum levels of cortisol and DHEA were found to be significantly elevated in PCOS compared to healthy women with a statistical significance of p = 0.001. The mean and standard deviation (SD) of cortisol and DHEA among PCOS women were found to be 395.84 ± 195.62 and respectively. On the other hand, the mean and SD of cortisol and DHEA among healthy controls were found to 256.26 ± 190.92 and 6.55 ± 4.66 correspondingly. Conclusion From this study, the stress hormone levels were found to be significantly distinct between the two groups. Stress could play a silent role in the pathogenesis of PCOS and its complications. Interventions to reduce stress among these women can considerably help to reduce the severity of existing symptoms as well as onset of dicey complications.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Stress and polycystic ovarian syndrome-a case control study among Indian women
- Date Crossref
- 01/07/2023
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Sri Ramachandra Institute of Higher Education and Research Departmeent of Reproductive Medicine and Surgery pays non établi dans la noticeUniversité ou école supérieure
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Central Council for Research in Yoga & Naturopathy pays non établi dans la noticeStructure de recherche
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MVJ Medical College and Research Hospital Department of Physiology pays non établi dans la noticeÉtablissement de santé
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Sri Ramachandra Medical College and Research Institute Department of Physiology pays non établi dans la noticeUniversité ou école supérieure
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Government Yoga and Naturopathy Medical College and Hospital Department of Biochemistry and Physiology pays non établi dans la noticeUniversité ou école supérieure
Departmeent of Reproductive Medicine and Surgery — Sri Ramachandra Institute of Higher Education and Research, Central Council for Research in Yoga & Naturopathy et Department of Physiology — MVJ Medical College and Research Hospital, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.