Central Retinal Artery Occlusion in COVID-Associated Mucormycosis
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Le résumé fourni par la source
Introduction: Significant surge of mucormycosis was reported in the Indian Subcontinent during the second wave of the COVID-19 pandemic. COVID-associated mucormycosis (CAM) was defined as the development of features of mucormycosis with prior or current history of COVID-19 infection. Rapid angioinvasion is an important characteristic of mucormycosis. Authors intended to find out the prevalence of retinal arterial occlusion and its association with vascular embolic occlusion elsewhere in the body among CAM patients in this study. Methods: This was an observational study. All consecutive-confirmed cases of mucormycosis ( n = 89) and age-/gender-/risk factor-matched controls ( n = 324) admitted in the designated COVID center were included in the study. All cases and controls underwent comprehensive ophthalmological, otorhinological, and neurological examinations. All necessary investigations to support the clinical diagnosis were done. Qualitative data were analyzed using the Chi-square test. Quantitative data for comparison of means between the cases and controls were done using unpaired t -test. Results: Twenty-one (23.59%) patients manifested the defined outcome of central retinal artery occlusion (CRAO). Among age-matched control, with similar diabetic status, none had developed the final outcome as defined ( P < 0.05). About 90.47% of subjects with CRAO presented with no perception of light vision. Thirteen subjects (61.9%) with the final outcome developed clinical manifestations of stroke during the course of their illness with radiological evidence of watershed infarction ( P = 0.001). Orbital debridement was performed in 9 (42.85%) subjects while orbital exenteration was done in 8 (38.09%) subjects. Conclusions: CRAO in CAM patients was found to have aggressive nature turning the eye blind in a very short period of time. CRAO can serve as a harbinger for subsequent development of more debilitating and life-threatening conditions such as stroke among CAM patients.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Central Retinal Artery Occlusion in COVID-Associated Mucormycosis
- Date Crossref
- 01/04/2023
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Bangur Institute of Neurosciences Department of Neurology pays non établi dans la noticeÉtablissement de santé
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Institute of Neurosciences Kolkata pays non établi dans la noticeÉtablissement de santé
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Creative Commons pays non établi dans la noticeOrganisation à but non lucratif
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AMRI Hospitals Department of Histopathology pays non établi dans la noticeÉtablissement de santé
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Medical College and Hospital pays non établi dans la noticeUniversité ou école supérieure
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Department of Ophthalmology pays non établi dans la noticeInstitution
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Department of Anatomy pays non établi dans la noticeInstitution
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Department of Pulmonary Medicine pays non établi dans la noticeInstitution
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Regional Institute of Ophthalmology Division of Orbit and Oculoplasty pays non établi dans la noticeStructure de recherche
Department of Neurology — Bangur Institute of Neurosciences, Institute of Neurosciences Kolkata et Creative Commons, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.