THE EFFECTIVENESS OF THE PHYTOTHERAPEUTIC DRUGKANEFRON® H (TRINEPHRON) IN THE TREATMENT OF GLOMERULONEPHRITIS REVIEW OF CLINICAL EXPERIENCE (literature review)

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The article highlights the use of a combination of data of plantsthat are part of the drug "Trinefron", which has diuretic, anti-inflammatory, antispasmodic, antioxidant and nephroprotective effects, reducing the permeability of capillaries in the mono- or combined use of its glomerulonephritis. Goal. To evaluate the healing properties of the components of trinephron on the human body, its role in the treatment of urinary tract infections, namely glomerulonephritis. Materials and methods. Statistical processing of data from foreign articles about the healing effect of a combined preparation from a goldenrod, mistress, rosemary for glomerulonephritis in MNONO therapy and combined treatment. The results of statistical studies revealed that the effectiveness of Kanefron H in the complex treatment of glomerulonephritis in the use of monotherapy didnot affect the immunological parameters and the ratio of subpopulationsCD4+/CD8+, but reduced the level of immune complexes. The assessment of the nephroprotective effects of the drug was detected, namely - normalization of diuresis and speed of glomerular filtration. According to [10], a significant decrease in leukocyturia is described, but the most positive effect is observed in thecombined therapy of prednisolone with canophron. Against the background of prednisolone there is an improvement in renal function with a decrease in protein, creatinine and urea in the blood. According to a randomized prospective study conducted by Dudar, etc.,there was a lower frequency of recurrence in patients with chronic recurrent pyelonephritis and cystitis, who were prevented by this remedy within 3 months after standard therapy. The maximum effect was found in patients who received a herbal remedy together with standard therapy in the acute phase of the disease. A similar study [4] in patients with type 2 diabetes with metabolic syndrome showed patients receiving herbal mixture for prevention for 3 months and for 6 months. The antiproteinuric effect is demonstrated in patients with microalbuminuria from low to moderately high levels. According to a one -center cohort study, published by CEBAN, among 237 patients with ureter stones up to 0.7 cm in diameter and without lesions of the urinary tract during the first 10 days of hospitalization when using combination treatment, higher rates of excretion of the renal. According to Gaibullaev's research (2008–2009) and Kariyev (in 2010–2011),most patients with idiopathic uncomplicated calcium-oxalate kidney stones in the fall and winter received treatment with a plant preparation on which a slightincrease in diurasis. Excretion with oxalate urine (significantly), calcium (trend)and citric acid (trend) decreased, but magnesium excretion has increased(significantly) during therapy. Conclusion. On the basis of the above, it was found that monotherapy partially normalizes urodynamics, has an antiproteinuric effect among patients with low andmoderately high microalbuminur

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.