Post COVID-19 Infection Psychosis: Could SARS-CoV-2 Virus Infection Be a Neuropsychiatric Condition That Triggers Psychotic Disorders? – A Case-Based Short Review

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Claudiu Ionut Vasile,1,2 Mihaela Camelia Vasile,1,3,* Monica Laura Zlati,4,5,* Elena Emanuela Herbei,6,* Lorena Lepădatu,7,* Cristina Munteanu,2,* Alexandru Nechifor,8,* Alin Laurențiu Tatu8– 10 1Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, România; 2“Elena Doamna” Clinical Hospital of Psychiatry, Galaţi, România; 3Infectious Diseases Department, Clinical Hospital of Infectious Diseases “Sf. Cuvioasa Parascheva”, Galați, România; 4Business Administration Department, Dunărea de Jos University, Galați, România; 5Accounting, Audit and Finance Department, Stefan Cel Mare University, Suceava, România; 6Department of Materials and Environmental Engineering, Centre of Nanostructures and Functional Materials, Faculty of Engineering, University “Dunărea de Jos”, Galaţi, România; 7“Sf Ap Andrei” Emergency County Clinical Hospital, Galați, România; 8Research Center in the Field of Medical and Pharmaceutical Sciences, ReFORM-UDJ, Galați, România; 9Dermatology Department, “Sf Cuv Parascheva” Clinical Hospital of Infectious Diseases, Galați, România; 10Multidisciplinary Integrated Center of Dermatological Interface Research MIC DIR, Dunărea de Jos” University, Galați, România*These authors contributed equally to this workCorrespondence: Mihaela Camelia Vasile; Elena Emanuela Herbei, “Dunărea de Jos”University, 47 Domnească Street, Galați, 800010, Romania, Tel +40724571976 ; +40723015307, Email mihaela272006@yahoo.com; elena.valcu@ugal.roAbstract: Corona virus (COVID-19) is an epidemy of respiratory disease caused by a novel corona virus and it was declared by the World Health Organization (WHO) to be a global health pandemic emergency. Due to the neuropsychiatric manifestation of Covid-19 that have been associated with psychotic disorders, in this paper we choose to present a case from “Elena Doamna” Psychiatric Hospital from Galati, Romania and to correlate it with other cases from literature in a mini review presentation. In our paper, we present the case of a patient of 44-year-old men, with no past psychiatric history whose behavior included psycho-motor agitation, perception and thinking disorders, disorganized behaviour, attempted suicide by stabbing. The last perspectives from the two years of pandemic together with psychiatric disease linked the virus infections with psychosis to the main concern that Covid-19 could determine psychiatric disorders. There were also presented same literature studies of patients with no personal pathological history in the psychiatric field which developed psychiatric disorders after COVID-19 infection. SARS-CoV-2 has a psychological impact on the mental health status of the worldwide and, especially when it is associated with psychotic symptoms and can affect the quality-of-life. In some cases, the virus affected the brain and as a result, the psychosis symptoms could be an emerging phenomenon associated with the corona virus. Based on the DSM V and ICD-10 criteria, the diagnosis was of acute psychiatric disorders with symptoms of schizophrenia (F23.1). The case report and review reliefs that there is a causal link between the SARS CoV-2 infection and mental disorders, which is currently being investigated.Keywords: COVID-19 pandemic, psychiatric disorders, DSM V and ICD-10 criteria

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