Supplementary Figures 1-7 from Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial–Stromal Tumors by Targeting PDGFR-β

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Supplementary Figure 1. Histologic evaluation of adenocarcinoma and NE tumors from TRAMP mice; Supplementary Figure 2. MCs infiltration in prostates of TRAMP mice; Supplementary Figure 3. OPT 7714 cells originate NE tumors in vivo; Supplementary Figure 4. Murine B16 F10 cells express cKit and PDGFR-β; Supplementary Figure 5. Human PC3 cells express cKit but are insensitive to Imatinib treatment; Supplementary Figure 6. Murine normal seminal vesicles do not express PDGFR-β; Supplementary Figure 7. Human phyllodes breast tumors express PDGFR-β.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.