Clinical Perspective on Human Immunodeficiency Virus Care of Ukrainian War Refugees in Poland
Rattachement africain : pl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: The Russian invasion of Ukraine forced migration for safety, protection, and assistance. Poland is the primary sheltering country for Ukrainian refugees, providing support including medical care, which resulted in the rapid ∼15% increase in the number of followed-up people with human immunodeficiency virus (HIV) (PWH) in the country. Here, we present the national experience on HIV care provided for refugees from Ukraine. METHODS: Clinical, antiretroviral, immunological, and virologic data from 955 Ukrainian PWH entering care in Poland since February 2022 were analyzed. The dataset included both antiretroviral-treated (n = 851) and newly diagnosed (n = 104) patients. In 76 cases, protease/reverse transcriptase/integrase sequencing was performed to identify drug resistance and subtype. RESULTS: Most (70.05%) of the patients were female, with a predominance of heterosexual (70.3%) transmissions. Anti-hepatitis C antibody and hepatitis B antigen were present in 28.7% and 2.9% of the patients, respectively. A history of tuberculosis was reported in 10.1% of cases. Among previously treated patients, the viral suppression rate was 89.6%; 77.3% of newly HIV diagnosed cases were diagnosed late (with lymphocyte CD4 count <350 cells/μL or AIDS). The A6 variant was observed in 89.0% of sequences. Transmitted mutations in the reverse transcriptase were found in 15.4% treatment-naive cases. Two patients with treatment failure exhibited multiclass drug resistance. CONCLUSIONS: Migration from Ukraine influences the characteristics of HIV epidemics in Europe, with an increase in the proportion of women and hepatitis C coinfected patients. Antiretroviral treatment efficacy among previously treated refugees was high, with new HIV cases frequently diagnosed late. The A6 subtype was the most common variant.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Clinical Perspective on Human Immunodeficiency Virus Care of Ukrainian War Refugees in Poland
- Date Crossref
- 08/03/2023
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Pomeranian Medical University Department of Infectious pays non établi dans la noticeUniversité ou école supérieure
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Medical University of Lodz Department of Infectious Diseases and Hepatology pays non établi dans la noticeUniversité ou école supérieure
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University of Szczecin pays non établi dans la noticeUniversité ou école supérieure
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Medical University of Warsaw pays non établi dans la noticeUniversité ou école supérieure
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Nicolaus Copernicus University pays non établi dans la noticeUniversité ou école supérieure
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Wroclaw Medical University Department of Infectious Diseases pays non établi dans la noticeUniversité ou école supérieure
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Jagiellonian University Department of Infectious and Tropical Diseases pays non établi dans la noticeUniversité ou école supérieure
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University of Warmia and Mazury in Olsztyn pays non établi dans la noticeUniversité ou école supérieure
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University of Zielona Góra pays non établi dans la noticeUniversité ou école supérieure
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Regional Hospital and Immune Deficiency pays non établi dans la noticeÉtablissement de santé
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Medical University in Warsaw Department of Infection pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Medicine Department of Infectious Diseases and Hepatology pays non établi dans la noticeUniversité ou école supérieure
Department of Infectious — Pomeranian Medical University, Department of Infectious Diseases and Hepatology — Medical University of Lodz et University of Szczecin, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.