Accès ouvert déclaré
2023
article
Assessment of Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months
Andrew J. Admon, Theodore J. Iwashyna, Lee A. Kamphuis, Stephanie Gundel, Sarina K. Sahetya, Ithan D. Peltan, Steven Y. Chang, Jin H. Han, Kelly C. Vranas, Kirby P. Mayer, Aluko A. Hope, Sarah E. Jolley, Ellen Caldwell, Max Monahan, Katrina Hauschildt, Samuel M. Brown, Neil R. Aggarwal, Bruce Thompson, Catherine L. Hough, Francois Abi Fadel, Michael S. Aboodi, Samuel Acquah, Jason Y. Adams, Narendrakumar Alappan, Timothy E. Albertson, Mohammed Al‐Jaghbeer, Eyad Almasri, James S. Andrews, Derek Angus, Jason V. Baker, Rebecca M. Baron, Michaël Baumann, Torben K. Becker, Michelle Biehl, Billie Bixby, Joseph Bledsoe, John W. Bloom, Somnath Bose, Katherine L. Boyle, Patrick J. Bradley, Rich D Branson, Ellen L. Burnham, Carolyn S. Calfee, Sean J. Callahan, Alessandro Cancelliere, Shannon S. Carson, Jonathan D. Casey, Sweta Chekuri, Peter Chen, Tina Chen, James Chenoweth, Philip J. Choi, Ivan Co, Sean P. Collins, Ana Carolina Monteiro, Mick P. Couper, Christopher E. Cox, Jonathan Daich, Marjolein de Wit, Ben P deBoisblanc, Matthew Dettmer, Sandipan Dhar, David Dillon, Sarah B. Doernberg, Pratik Doshi, Ivor S. Douglas, Brian E. Driver, Siddharth Dugar, Abhijit Duggal, Marie‐Carmelle Elie, Kyle B. Enfield, John Eppensteiner, Daniel Fein, Michael R. Filbin, Clark Files, James H. Finigan, Alexander H. Flannery, Andrea S. Foulkes, Alpha A. Fowler, Adam Frisch, Monica Fung, J Gaillard, James Galbraith, Sheetal Gandotra, Jayna Gardner-Gray, Elizabeth A. Gay, Kevin W. Gibbs, Evanpaul Gill, Adit A. Ginde, Timothy D. Girard, Pauline H. Go, Neha Goel, Ewan C. Goligher, Jose Gomez‐Arroyo, Michelle N. Gong, Andrew Goodwin, Richard D. Gordon, Colin K. Grissom, Kyle J. Gunnerson, Tarik Hanane, Christopher K. Hansen, Kyle Happel, Estelle S. Harris, Jason S. Haukoos, Gregory W. Hendey, Carolyn M. Hendrickson, Kathryn A. Hibbert, Ellie Hirshberg, R. Duncan Hite, J. Jason Hoth, Peter C. Hou, Terri Hough, Judie A. Howrylak, David T. Huang, Kristin Hudock, Ryan Huebinger, Gina Hurst, Cameron Hypes, Robert C. Hyzy, Nicole M. Iovine, Marjan Islam, Jennifer Israel, Jack Iwashyna, Faraz Jaffer, William J. Janssen, Namita Jayaprakash, Shijing Jia, Nicholas J. Johnson, Alan E. Jones, Elizabeth Jones B Jones, Alex Kadl, Kirsten N. Kangelaris, Markos Kashiouris, Lawrence E. Kass, Marla J. Keller, Akram Khan, Mehdi Khosravi, Hassan Khouli, Harish Kinni, Michael E. Kiyatkin, Daniel Knox, Amita Krishnan, Nicholas Kurtzman, Matthew R. Lammi, Michael J. Lanspa, Viet T. Le, Lindsay Leither, Joseph E. Levitt, M. L'Heureux, George Lim, Alexander T. Limkakeng, Michael Lin, Christopher J. Lindsell, Kathleen D. Liu, Kenneth Lyn-Kew, Patrick G. Lyons, Fraser Mackay, Patrick Maher, Simon A. Mahler, Anita Malhotra, Brian Malley, Michael A. Matthay, Teresa May, Katherine Mayer, Jakob I. McSparron, Bryan J. McVerry, Chadwick D. Miller, Stephen P. Miller, Steven C Minear, Eduardo Mireles, Jason R. Mock, Amira Mohamed, Ashley Montgomery-Yates, Peter E. Morris, Jarrod Mosier, Ari Moskowitz, Marc Moss, Simon Mucha, Elizabeth Munroe, Rahul Nair, Utsav Nandi, Denise Nassisi, William Nkemdirim, D. Norton, Brian O’Gara, Daniel J. O’Hearn, Darragh Shane OMahony, David B. Page, Robert Paine, Pauline K. Park, Sara Pasha, Gabriel D Patarroyo Aponte, Avignat S. Patel, Bela Patel, Sarah M. Perman, Jacqueline Marie Pflaum-Carlson, Simone Phang-Lyn, Víctor Pinto-Plata, Matthew E. Prekker, Mike Puskarich, Nida Qadir, Raju Reddy, Todd W. Rice, Lynne D. Richardson, Richard R. Riker, Emanuel P. Rivers, Bryce R. H. Robinson, Angela J. Rogers, Derek W. Russell, Debasis Sahoo, Christian Sandrock, Shane Sanne, R.G. Scheraga, Eric Schmidt, Jordan B Schooler, K. Schwab, Wesley H. Self, Matthew W. Semler, Paulina Sergot, Faraaz Shah, Nate Shapiro, Daniel L Shaw, Robert Sherwin, Matthew Siuba, Michael W. Sjoding, Howard Smithline, Mark Sochor, John R. Spurzem, Vasisht Srinivasan, Tessa L. Steel, Jay S. Steingrub, Bryan Stenson, Sarah A. Sterling, Jason P. Stopyra, William-May B Stubblefield, Jeffrey M. Sturek, Jamie Sturgill, Jennifer Swiderek, Aamer Syed, Daniel Talmor, Geneva Tatem, Nirosshan Thiruchelvam, Thompson Tg, Melissa L. Thompson Bastin, Mark Tidswell, Sam Torbati, Stacy A. Trent, Terren Trott, Thomas E. Van der Kloot, Bonnie Wang, Ralph C. Wang, Lorraine B. Ware, Christopher M. Waters, Alexandra Weissman, Katherine D. Wick, Aimee Wilkin, David M. Wilson, Jenny G Wilson, David Wyles, Joseph H. Yanta, Donald M. Yealy, Scott T. Youngquist, Tanzira Zaman
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20Institutions déclarées
1Pays d’affiliation déclarés
Résumé fourni par la source
Importance: Individuals who survived COVID-19 often report persistent symptoms, disabilities, and financial consequences. However, national longitudinal estimates of symptom burden remain limited. Objective: To measure the incidence and changes over time in symptoms, disability, and financial status after COVID-19-related hospitalization. Design, Setting, and Participants: A national US multicenter prospective cohort study with 1-, 3-, and 6-month postdischarge visits was conducted at 44 sites participating in the National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Network's Biology and Longitudinal Epidemiology: COVID-19 Observational (BLUE CORAL) study. Participants included hospitalized English- or Spanish-speaking adults without severe prehospitalization disabilities or cognitive impairment. Participants were enrolled between August 24, 2020, and July 20, 2021, with follow-up occurring through March 30, 2022. Exposure: Hospitalization for COVID-19 as identified with a positive SARS-CoV-2 molecular test. Main Outcomes and Measures: New or worsened cardiopulmonary symptoms, financial problems, functional impairments, perceived return to baseline health, and quality of life. Logistic regression was used to identify factors associated with new cardiopulmonary symptoms or financial problems at 6 months. Results: A total of 825 adults (444 [54.0%] were male, and 379 [46.0%] were female) met eligibility criteria and completed at least 1 follow-up survey. Median age was 56 (IQR, 43-66) years; 253 (30.7%) participants were Hispanic, 145 (17.6%) were non-Hispanic Black, and 360 (43.6%) were non-Hispanic White. Symptoms, disabilities, and financial problems remained highly prevalent among hospitalization survivors at month 6. Rates increased between months 1 and 6 for cardiopulmonary symptoms (from 67.3% to 75.4%; P = .001) and fatigue (from 40.7% to 50.8%; P < .001). Decreases were noted over the same interval for prevalent financial problems (from 66.1% to 56.4%; P < .001) and functional limitations (from 55.3% to 47.3%; P = .004). Participants not reporting problems at month 1 often reported new symptoms (60.0%), financial problems (23.7%), disabilities (23.8%), or fatigue (41.4%) at month 6. Conclusions and Relevance: The findings of this cohort study of people discharged after COVID-19 hospitalization suggest that recovery in symptoms, functional status, and fatigue was limited at 6 months, and some participants reported new problems 6 months after hospital discharge.
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Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Assessment of Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months
- Date Crossref
- 14/02/2023
- Éditeur
- American Medical Association (AMA)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Sujets associés
Long-Term Effects of COVID-19COVID-19 Clinical Research StudiesCOVID-19 and healthcare impacts