172. Bos taurus and Bos indicus reduced representation bisulfite sequencing comparison showed high epigenetic variability in Bos subspecies

Le résumé fourni par la source

Bos indicus and Bos taurus subspecies possess distinct morphological traits as a consequence of artificial selection and environmental adaptation. However, the impact of epigenetic contribution in relation to breed adaptation in the two subspecies has not been explored. In this work, Reduced Representation Bisulfite Sequencing (RRBS) profiling of the indicine Nellore (N) and the taurine Angus (A) cattle breeds was compared to identify CpG methylation differences in the two subspecies. A total of 134,553 methylated regions (MRs) were detected across all 20 samples (5 N and 5 A in two seasons). Approximately one third of them show differences in the two breeds in genes which function is related to sensory perception of chemical stimulus, development process and regulation of cellular organization. Further investigation is necessary to understand the real impact of epigenetic differences in the two breeds and how they can regulate genes important for cattle adaptation.

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