Validation of the French version of the THYCA-QoL questionnaire for the health-related quality of life in thyroid cancer patients.

Le résumé fourni par la source

Abstract Background: Health-related quality of life (HRQoL) is an important outcome in oncology. In our previous work, the specific questionnaire to evaluate the HRQoL for thyroid cancer, the THYCA-QoL, has been translated into French. In this work we aimed to validate the psychometric properties of the French version of the THYCA-QoL questionnaire (F-THYCA-QoL). Methods: The F-THYCA-QoL is composed of 24 items and is divided into 7 dimensions and 6 single items. The F-THYCA-QoL and QLQ-C30 of the European Organisation for Research and Treatment of Cancer (EORTC) were mailed to thyroid cancer patients undergoing surgery. Data from responders obtained was used to test acceptability, reliability and validity of the F-THYCA-QoL questionnaire. Results: Among contacted patients, 280 patients of the University Institute of Face and Neck of Nice responded to the questionnaire between January 2015 and January 2019. The low number of missing data (0.007%) showed a good acceptability of the questionnaire. Six of the 7 items exhibited a good internal consistency with a Cronbach’s alpha ≥ 0.70. No floor or ceiling effects were observed. Factorial validity was demonstrated for 5 scales out of 7, using a multitrait-multimethod analysis and an exploratory factor analysis. Criterion validity assessed between the F-THYCA-QoL and QLQ-C30 was satisfactory. Conclusion: The F-THYCA-QoL questionnaire is a reliable and valid assessment tool that used with the EORTC QLQ-C30 allows to evaluate the HRQoL of thyroid cancer patient in France.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.