A Nonconventional Analysis of CD$4^{+}$ and CD$8^{+}$ T Cell Responses\n During and After Acute Lymphocytic Choriomeningitis Virus Infection

Le résumé fourni par la source

A mathematical model from a previous work was re-fitted and analyzed for\nexperimental data regarding the cellular immune response to the lymphocytic\nchoriomeningitis virus. Specifically, the $CD8^{+}$ T cell response to six MHC\nclass I-restricted epitopes (GP* and NP*) and $CD4^{+}$ T cell responses to two\nMHC class II-restricted epitopes\\cite{de2003different}. In this work, we use\ncalibration through log likelihood maximization to investigate if different\nparameters can produce a more accurate fit of the model presented previously in\nthe paper titled \\textit{Different Dynamics of CD$4^{+}$ and CD$8^{+}$ T Cell\nResponses During and After Acute Lymphocytic Choriomeningitis Virus\nInfection}\\cite{de2003different}\n

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