Electrospun Polyacrylonitrile Silver Nanoparticle (PAN-AgNP) Nanocomposites as Alternative Antimicrobial Materials
Rattachement africain : tw, ye. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Infectious microbial diseases can easily be transferred from person to person in the air or via high contact surfaces. As a result, researchers must aspire to create materials that can be implemented in surface contact applications to disrupt pathogen growth and transmission. Silver (Ag) is known to possess antimicrobial activity and has been used in the past in various pharmaceutical applications. Herein, we examine the antimicrobial properties of polyacrylonitrile (PAN) nanofibers coated with different concentrations of silver nanoparticles (AgNPs). Polyacrylonitrile (PAN) was homogenized with varied weight concentrations of silver nitrate (AgNO3) in N,N-Dimethylformamide (DMF) solution, a common organic solvent that serves as both an electrospinning solvent and as a reducing agent that forms AgNPs. The subsequent colloids were electrospun into nanofibers, which were then characterized via various analysis techniques, including Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Energy Dispersive X-Ray (EDX) Analysis, Dynamic Light Scattering (DLS), and X-Ray Photoelectron Spectroscopy (XPS). 10 microbes, including 7 strains of Gram-positive bacteria, 2 strains of Gram-negative bacteria, and Candida albicans were incubated with cutouts of various PAN-AgNP nanocomposites using disk diffusion methods to test for the nanocomposites’ antimicrobial efficiency. We report that PAN-AgNP nanocomposites retain a certain degree of antimicrobial longetivity; samples stored for approximately 90 days demonstrate similar antimicrobial activity against Escherichia coli (E. coli) and Lactobacillus crispatus (L. crispatus) when compared to their newly electrospun counterparts. Moreover, our results indicate that PAN-AgNP nanocomposites successfully display antimicrobial activity against various bacteria and fungi strains regardless of their resistance to conventional antibiotics. Our study demonstrates that PAN-AgNP nanocomposites can potentially be applied to surfaces at risk of contracting microbial infections.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Electrospun Polyacrylonitrile Silver Nanoparticle (PAN-AgNP) Nanocomposites as Alternative Antimicrobial Materials
- Date Crossref
- 23/09/2022
- Éditeur
- American Chemical Society (ACS)
- Type
- posted-content
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Taipei American School pays non établi dans la noticeUniversité ou école supérieure
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University of Science and Technology Department and Graduate Institute of Aquaculture pays non établi dans la noticeUniversité ou école supérieure
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National Kaohsiung University of Science and Technology pays non établi dans la noticeUniversité ou école supérieure
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Chang Gung University Department of Radiation Oncology pays non établi dans la noticeUniversité ou école supérieure
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Kaohsiung Chang Gung Memorial Hospital pays non établi dans la noticeÉtablissement de santé
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Kaohsiung Medical University pays non établi dans la noticeUniversité ou école supérieure
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Department of Scientific Research pays non établi dans la noticeInstitution
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School of Traditional Chinese Medicine pays non établi dans la noticeUniversité ou école supérieure
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School of Pharmacy pays non établi dans la noticeUniversité ou école supérieure
Taipei American School, Department and Graduate Institute of Aquaculture — University of Science and Technology et National Kaohsiung University of Science and Technology, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.