345.7: Nutritional Diagnosis in Chronic Intestinal Failure Patients: GLIM Criteria vs Subjective Global Assessment

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Introduction: Parenteral Nutrition (PN) is the main support in Chronic Intestinal Failure (CIF) patients. As part of their regular evaluation, nutritional assessment is usually done through Subjective Global Assessment (SGA). The Global Leadership Initiative on Malnutrition (GLIM) developed phenotypic and etiologic criteria for assessing and grading malnutrition. The aims of this study were to compare these tools in nutritional assessment of CIF patients and determine the severity of malnutrition according to GLIM´s phenotypic criteria. Methods: From June 2019 through December 2021 a retrospective analysis was conducted. All patients included had CIF diagnosis. Malnutrition was evaluated using SGA and GLIM criteria at the first office visit, while the degree of malnutrition was assessed according to phenotypic criteria. Descriptive, bivariate, multiple logistic regression and ROC analysis were performed. Results: Seventy adult patients with CIF were included. Forty-two (60%) had short bowel syndrome. Mean age was 47.76 years and 51.4% were female. Nutritional status using SGA showed 40% patients well nourished, 27% moderately or suspected of being malnourished, and 33% severely malnourished. When using GLIM criteria, 60 patients (86%) presented at least 1 phenotypic criteria of malnutrition. In terms of etiologic criteria all patients had reduced food intake and/or impaired absorption or food assimilation. When grading malnutrition status 53% of patients had moderate and 33% severe malnutrition. The ROC analysis showed an area under the curve of 0.92 when SGA was analyzed and 0.86 for GLIM criteria (p = 0.98). (Figures 1 and 2) Conclusion: Nutritional assessment in CIF patients is mandatory to improve malnutrition, if present. In this study GLIM criteria showed a higher percentage of patients with malnutrition, but when comparing ROC analyses not statically difference between SGA/GLIM was shown.

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