P8.022: Structured Diabetes Education: Significance Among Kidney Transplants Recipients With Post-transplant Diabetes

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Introduction: Diabetes knowledge among kidney transplant recipients with post-transplant diabetes (NODAT) is not evaluated comprehensively. Aim of the study: We aimed to evaluate the impact of structured diabetes education on the development of diabetic micro-and macro-angiopathies in kidney transplant recipients with new-onset diabetes after transplant. Patients and methods: In this prospective randomized controlled trial, we categorized 210 kidney transplants recipients with NODAT into two groups according to the type of diabetes education (in a ratio of 2:1). Group 1 (n=140) received structured diabetes education while group 2(n=70) received conventional education. We collected patients’ data in patient identification and metabolic control parameters. Results: Most patients in the two groups (1&2) were Kuwaiti (60.7 vs. 58.6%), men (57.9 vs. 68.6%), with high school education levels (43.6vs.48.6%). The minority of patients were smokers (12.9 vs.8.7%), and chronic glomerulonephritis was the original disease in 36.4 vs. 35.4% in the two groups, respectively. Most of the enrolled patients (72.8 vs. 78.6%) underwent hemodialysis pre-transplant. At the start of the study, the percentage of patients with diabetic neuropathy was comparable in both groups (32.4 vs. 27.6% in the two groups respectively) and after 24 months, follow up electromyography/nerve conduction did not show a significant difference between the studied groups(P>0.05). Similarly, the number of patients with fundus imaging showing retinopathy was comparable in both groups at the study’s start and end (p>0.05). Also, macroangiopathic events (cerebral stroke, acute myocardial infection, or peripheral arterial disease) were higher in group 1 but did not rank to significance (p>0.05). On the other hand, although the percentage of patients with nephropathy was comparable in both groups at the start of the study, this percentage decreased significantly in group 1 after 24 months of the study compared to group 2 and the basal value in the same group(p=0.016). Conclusion: Structured diabetes education is associated with reducing diabetic nephropathy but without significant impact on other micro- or macroangiopathy. We recommended being delivered to all diabetic kidney transplant recipients

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