COVID-19 enfeksiyonunun erkek cinsel fonksiyonları üzerindeki etkisi ve risk faktörleri

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OBJECTIVE:The objective of this study is to investigate the sexual dysfunction(SD) occurring after COVID-19 disease and possible risk factors.MATRERIAL and METHODS: This is the first longitudinal study comparing the sexual health of males, prior and latter to PCR confirmed COVID-19 diagnosis using the all domains of International index of erectile function-15 (IIEF-15) questionnaire and investigating the risk factors for SD.Between 2020-2021, 114 male patients were included and surveyed by IIEF-15 twice, at the time of diagnosis and after 3 months.RESULTS: Median age was 49 years (IQR: 29-58.5).Median IIEF-EF score decreased (24 to 20,p=0.001) and there was also a statistically significant decline in all domains of IIEF-15 including orgasm (9 to 8,p=0.01),sexual desire (8 to 7,p=0.001),sexual satisfaction (11 to 8,p=0.001) and over satisfaction (8 to 7,p=0.001).Patients with an IIEF-EF decrease > 4 (n=27, 23.7%) had significantly higher rates of diabetes (37% vs 13.8%, p=0.01), hypertension (40.7% vs 20.7%, p=0.04), smoking (40.7% vs 20.7%, p=0.04),COVID-19 pneumonia (44.4% vs 23.0%, p=0.03) and lower rates of fatigue (66.7% vs 86.2%, p=0.02) than the other group Pneumonia (OR: 3.55,p=0.02),and fatigue (OR: 0.22,p=0.01)were significant independent risk factors of minimally clinically significant IIEF-EF decrease (>4).CONCLUSION: COVID-19 cases may present with urologic symptoms to our outpatient clinics.The disease causes deterioration in all aspects of sexual function, including erectile function, orgasm, sexual desire and satisfaction of the patients.A third of patients face a decrease of one rank in erectile dysfunction severity.Pneumonia and fatigue symptoms are significant risk factors of post-COVID-19 erectile dysfunction.Pneumonia, urinary urgency symptom and diabetes mellitus increase the risk of deterioration in IIEF domains besides erectile function.Endothelial dysfunction may be one of the causes of post COVID-19 sexual function decline..

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