High mortality at the beginning of the COVID-19 pandemic in a referral center in the metropolitan area of Mexico City
Rattachement africain : mx. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
INTRODUCTION: There is limited information about the coronavirus disease 2019 (COVID-19) disease in Latin-American countries. Our objective was to describe the clinical characteristics and outcomes of COVID-19 patients in Mexico. METHODOLOGY: We conducted a retrospective cohort study with 333 consecutive patients who were admitted to Hospital de Especialidades "Dr. Antonio Fraga Mouret" in Mexico City with COVID-19 between April 1, 2020, and June 30, 2020. Demographic, clinical, laboratory data, treatment details and 30-day outcomes were analyzed. RESULTS: The patients studied included 52% men (172/233) and the median age was 45 years. Up to 75% (250/333) of patients were classified as overweight or obese. There were 185 (56%) inpatients; 85% (158/185) were hospitalized in the general ward, and 15% (27/185) in the Intensive Care Unit (ICU). Laboratory measurements showed significant differences between inpatients and outpatients such as lymphocyte-count (median 0.8 vs 1.2×109/L, p < 0.001), LDH (median 650 vs 294 U/L, p < 0.001), CRP (median 147 vs 5 mg/L, p = 0.007), CK-MB (median, 15 vs 10 U/L, p = 0.008), ferritin (median, 860 vs 392 ng/mL, p = 0.02), and D-dimer (median, 780 vs 600 ng/mL, p = 0.15). These differences were seen between survivor and non-survivor patients as well. The rate of death in mechanically ventilated patients was 94% (67/71). Mortality at 30-day follow-up was 57% (105/185). CONCLUSIONS: We observed that majority of the non-survivors were obese and young. Complications leading to death was observed in majority of the cases.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- High mortality at the beginning of the COVID-19 pandemic in a referral center in the metropolitan area of Mexico City
- Date Crossref
- 30/08/2022
- Éditeur
- Journal of Infection in Developing Countries
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán pays non établi dans la noticeStructure de recherche
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Mexican Social Security Institute pays non établi dans la noticeOrganisme public
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Centro Médico Nacional La Raza pays non établi dans la noticeÉtablissement de santé
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Hospital de Especialidades Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Institute for Social Security and Services for State Workers pays non établi dans la noticeOrganisme public
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National Institute of Medical Science and Nutrition Salvador Zubiran Department of Infectious Disease pays non établi dans la noticeStructure de recherche
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National Medical Center November 20 ISSTE Department of Infectious Diseases pays non établi dans la noticeÉtablissement de santé
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexican Social Security Institute et Centro Médico Nacional La Raza, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.