Urge intolerance predicts tic severity and impairment among adults with Tourette syndrome and chronic tic disorders
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Le résumé fourni par la source
Background: Individuals with Tourette Syndrome and Persistent Tic Disorders (collectively TS) often experience premonitory urges-aversive physical sensations that precede tics and are temporarily relieved by tic expression. The relationship between tics and premonitory urges plays a key role in the neurobehavioral treatment model of TS, which underlies first-line treatments such as the Comprehensive Behavioral Intervention for Tics (CBIT). Despite the efficacy of CBIT and related behavioral therapies, less than 40% of adults with TS respond to these treatments. Further examination of the relationship between premonitory urges, tic severity, and tic impairment can provide new insights into therapeutic targets to optimize behavioral treatment outcomes. This study examined whether urge intolerance-difficulty tolerating premonitory urges-predicted tic severity and tic-related impairment among adults with TS. Methods: Participants were 80 adults with TS. Assessments characterized premonitory urge, distress tolerance, tic severity, and tic impairment. We used structural equation modeling (SEM) to examine the construct of urge intolerance-comprised of premonitory urge ratings and distress tolerance ratings. We first evaluated a measurement model of urge intolerance through bifactor modeling, including tests of the incremental value of subfactors that reflect premonitory urge severity and distress tolerance within the model. We then evaluated a structural model where we predicted clinician-rated tic severity and tic impairment by the latent variable of urge intolerance established in our measurement model. Results: Analyses supported a bifactor measurement model of urge intolerance among adults with TS. Consistent with theoretical models, higher levels of urge intolerance predicted greater levels of clinician-rated tic severity and tic impairment. Conclusion: This investigation supports the construct of urge intolerance among adults with TS and distinguishes it from subcomponents of urge severity and distress tolerance. Given its predictive relationship with tic severity and tic impairment, urge intolerance represents a promising treatment target to improve therapeutic outcomes in adults with TS.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Urge intolerance predicts tic severity and impairment among adults with Tourette syndrome and chronic tic disorders
- Date Crossref
- 10/08/2022
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Johns Hopkins University Department of Psychiatry and Behavioral Sciences pays non établi dans la noticeUniversité ou école supérieure
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Texas State University Department of Psychology pays non établi dans la noticeUniversité ou école supérieure
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Stanford University Department of Psychiatry and Behavioral Sciences pays non établi dans la noticeUniversité ou école supérieure
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University of California pays non établi dans la noticeUniversité ou école supérieure
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Marquette University Department of Psychology pays non établi dans la noticeUniversité ou école supérieure
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Suffolk University Department of Psychology pays non établi dans la noticeUniversité ou école supérieure
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Cornell University pays non établi dans la noticeUniversité ou école supérieure
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Northwestern University Department of Psychiatry and Behavioral Sciences pays non établi dans la noticeUniversité ou école supérieure
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UCLA Semel Institute for Neuroscience and Human Behavior Division of Child and Adolescent Psychiatry pays non établi dans la noticeStructure de recherche
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Department of Psychiatry pays non établi dans la noticeInstitution
Department of Psychiatry and Behavioral Sciences — Johns Hopkins University, Department of Psychology — Texas State University et Department of Psychiatry and Behavioral Sciences — Stanford University, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.