Meta-Analysis: Outcomes of Surgical and Medical Management of Diabetic Foot Osteomyelitis
Rattachement africain : us, au. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract Background The aim of this study was to evaluate clinical outcomes in the published literature on medical and surgical management of diabetic foot osteomyelitis (DFO). Methods A PubMed and Google Scholar search of articles relating to DFO was performed over the dates of January 1931 to January 2020. Articles that involved Charcot arthropathy, case reports, small case series, review articles, commentaries, nonhuman studies, and non-English articles were excluded. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool was used to rate the bias of each study. A meta-analysis was performed using random-effects and inverse variance methods. The search yielded 1192 articles. After review and the removal of articles that did not meet inclusion criteria, 28 articles remained. Eighteen articles were related to the medical management of DFO and 13 articles were related to surgical management. Three articles looked at a combination of medical and surgical management and were included in both groups. Heterogeneity was evaluated using Cochran Q, I2, τ2, and τ. Results The average success rate was 68.2% (range, 17.0%–97.3%) for medical treatment and 85.7% (range, 65.0%–98.8%) for surgical and medical treatment. There were significant inconsistencies in accounting for peripheral arterial disease and peripheral neuropathy. There was significant heterogeneity in outcomes between studies. However, there was a high rate of successful treatment and a wide range between patients with medical treatment and combined surgical and medical treatment. Conclusions Additional properly designed prospective studies with gold-standard references for diagnosing osteomyelitis are needed to help determine whether medical management of DFO can be successful without surgical intervention.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Meta-Analysis: Outcomes of Surgical and Medical Management of Diabetic Foot Osteomyelitis
- Date Crossref
- 09/08/2022
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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VA North Texas Health Care System pays non établi dans la noticeÉtablissement de santé
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The University of Texas Southwestern Medical Center Department of Orthopaedic Surgery pays non établi dans la noticeÉtablissement de santé
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Camden and Campbelltown Hospitals pays non établi dans la noticeÉtablissement de santé
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South Western Sydney Local Health District pays non établi dans la noticeOrganisme public
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Western Sydney University pays non établi dans la noticeUniversité ou école supérieure
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Surgical Service pays non établi dans la noticeInstitution
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Medical Service pays non établi dans la noticeInstitution
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School of Medicine Infectious Disease and Microbiology pays non établi dans la noticeUniversité ou école supérieure
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South West Sydney Limb Preservation and Wound Research Academic Unit pays non établi dans la noticeInstitution
VA North Texas Health Care System, Department of Orthopaedic Surgery — The University of Texas Southwestern Medical Center et Camden and Campbelltown Hospitals, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.