Optical Hemodynamic Imaging of Jugular Venous Dynamics During Altered\n Central Venous Pressure
Résumé fourni par la source
An optical imaging system is proposed for quantitatively assessing jugular\nvenous response to altered central venous pressure. The proposed system\nassesses sub-surface optical absorption changes from jugular venous waveforms\nwith a spatial calibration procedure to normalize incident tissue illumination.\nWidefield frames of the right lateral neck were captured and calibrated using a\nnovel flexible surface calibration method. A hemodynamic optical model was\nderived to quantify jugular venous optical attenuation (JVA) signals, and\ngenerate a spatial jugular venous pulsatility map. JVA was assessed in three\ncardiovascular protocols that altered central venous pressure: acute central\nhypovolemia (lower body negative pressure), venous congestion (head-down tilt),\nand impaired cardiac filling (Valsalva maneuver). JVA waveforms exhibited\nbiphasic wave properties consistent with jugular venous pulse dynamics when\ntime-aligned with an electrocardiogram. JVA correlated strongly (median,\ninterquartile range) with invasive central venous pressure during graded\ncentral hypovolemia (r=0.85, [0.72, 0.95]), graded venous congestion (r=0.94,\n[0.84, 0.99]), and impaired cardiac filling (r=0.94, [0.85, 0.99]). Reduced JVA\nduring graded acute hypovolemia was strongly correlated with reductions in\nstroke volume (SV) (r=0.85, [0.76, 0.92]) from baseline (SV: 79$\\pm$15 mL, JVA:\n0.56$\\pm$0.10 a.u.) to -40 mmHg suction (SV: 59$\\pm$18 mL, JVA: 0.47$\\pm$0.05\na.u.; p$<$0.01). The proposed non-contact optical imaging system demonstrated\njugular venous dynamics consistent with invasive central venous monitoring\nduring three protocols that altered central venous pressure. This system\nprovides non-invasive monitoring of pressure-induced jugular venous dynamics in\nclinically relevant conditions where catheterization is traditionally required,\nenabling monitoring in non-surgical environments.\n
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.