Diabetes is an independent predictor of severe acute pancreatitis

Le résumé fourni par la source

We aimed to determine the effect of diabetes mellitus (DM) on the severity of acute pancreatitis (AP) and whether diabetes is a predictor of severe acute pancreatitis (SAP). A total of 181 patients diagnosed with a first attack of AP in our hospital were retrospectively evaluated. AP severity was evaluated and compared between diabetic and non-diabetic patients. Independent factors predicting SAP were identified with a binary logistic regression model. Of the 164 patients [108 (65.9%) women, 56 (34.1%) men] enrolled in the study, 35 patients (21.3%) had been diagnosed with DM, while 129 (78.7%) did not have DM. SAP, necrotizing pancreatitis, and local complications were observed to be more common among diabetic patients compared to non-diabetic patients (all P < 0.001), while the incidences of systemic complications and transient or persistent organ failure were similar between the groups. The incidences of DM and cancer were higher in the SAP group (P < 0.001 and P = 0.033, respectively). The presence of DM (OR: 3.246, 95% CI: 1.278–8.244, P = 0.013), high (≥3) Ranson score (OR: 3.529, 95% CI: 1.342–9.280, P = 0.011), and high maximum C-reactive protein level (OR: 1.005, 95% CI: 1.001–1.010, P = 0.046) were independent risk factors predicting SAP. DM is both a risk factor for SAP and an independent predictor of SAP. Evaluation of the presence of DM at the time of diagnosis can help predict SAP in a considerably early phase.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.